About the Authors

Maren Reimer

Contributed equally to this work with: Maren Reimer, Torge Rempe

Affiliation Division of Neurological Pain Research and Therapy, Department of Neurology, University Hospital of Schleswig-Holstein, Campus Kiel, Germany

Torge Rempe

Contributed equally to this work with: Maren Reimer, Torge Rempe

Affiliation Division of Neurological Pain Research and Therapy, Department of Neurology, University Hospital of Schleswig-Holstein, Campus Kiel, Germany

Carolina Diedrichs

Affiliation Division of Neurological Pain Research and Therapy, Department of Neurology, University Hospital of Schleswig-Holstein, Campus Kiel, Germany

Ralf Baron

Affiliation Division of Neurological Pain Research and Therapy, Department of Neurology, University Hospital of Schleswig-Holstein, Campus Kiel, Germany

Janne Gierthmühlen

j.gierthmuehlen@neurologie.uni-kiel.de

Affiliation Division of Neurological Pain Research and Therapy, Department of Neurology, University Hospital of Schleswig-Holstein, Campus Kiel, Germany

Competing Interests

Torge Rempe and Carolina Diedrichs report no conflicts of interests. Maren Reimer received travel grants from Astellas, Grünenthal and Pfizer and research support from Mundipharma. Janne Gierthmühlen received honoraria as a speaker from Pfizer and travel grants from Pfizer and Grünenthal and is a consultant for Glenmark pharma. Ralf Baron reports current grant/Research Support by Pfizer, Genzyme, Grünenthal, Mundipharma. Member of the IMI "Europain" collaboration and industry members of this are: Astra Zeneca, Pfizer, Esteve, UCB-Pharma, Sanofi Aventis, Grünenthal, Eli Lilly and Boehringer Ingelheim, German Federal Ministry of Education and Research (BMBF): German Research Network on Neuropathic Pain, NoPain system biology, German Research Foundation (DFG). He received honoraria as a speaker from Pfizer, Genzyme, Grünenthal, Mundipharma, Sanofi Pasteur, Medtronic, Eisai, Lilly, Boehringer Ingelheim, Astellas, Desitin, Teva Pharma, Bayer-Schering, MSD and is a consultant for Pfizer, Genzyme, Grünenthal, Mundipharma, Allergan, Sanofi Pasteur, Medtronic, Eisai, Lilly, Boehringer Ingelheim, Astellas, Novartis, Bristol-Myers Squibb, Biogenidec, AstraZeneca, Merck, Abbvie, Daiichi Sankyo and Glenmark Pharmaceuticals. This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials. There are no conflicts of interests relevant to this article.

Author Contributions

Conceived and designed the experiments: JG. Performed the experiments: CD. Analyzed the data: MR TR JG. Wrote the paper: MR TR RB JG.