A Pharmacovigilance Approach for Post-Marketing in Japan Using the Japanese Adverse Drug Event Report (JADER) Database and Association Analysis

Masakazu Fujiwara; Yohei Kawasaki; Hiroshi Yamada

doi:10.1371/journal.pone.0154425

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Open Access

Peer-reviewed

Research Article

A Pharmacovigilance Approach for Post-Marketing in Japan Using the Japanese Adverse Drug Event Report (JADER) Database and Association Analysis

Masakazu Fujiwara ,

* E-mail: masakazu.fujiwara@shionogi.co.jp

Affiliations Department of Drug Evaluation & Informatics, Graduate school of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan, Department of Biostatistics, Shionogi Pharmaceutical Company, Osaka, Japan
⨯
Yohei Kawasaki,

Affiliation Department of Drug Evaluation & Informatics, Graduate school of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan
⨯
Hiroshi Yamada

Affiliation Department of Drug Evaluation & Informatics, Graduate school of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan
⨯

A Pharmacovigilance Approach for Post-Marketing in Japan Using the Japanese Adverse Drug Event Report (JADER) Database and Association Analysis

Masakazu Fujiwara,
Yohei Kawasaki,
Hiroshi Yamada

Published: April 27, 2016
https://doi.org/10.1371/journal.pone.0154425

About the Authors

Masakazu Fujiwara

* E-mail: masakazu.fujiwara@shionogi.co.jp

Affiliations Department of Drug Evaluation & Informatics, Graduate school of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan, Department of Biostatistics, Shionogi Pharmaceutical Company, Osaka, Japan

Yohei Kawasaki

Affiliation Department of Drug Evaluation & Informatics, Graduate school of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan

Hiroshi Yamada

Affiliation Department of Drug Evaluation & Informatics, Graduate school of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan

Competing Interests

Masakazu Fujiwara is employed by Shionogi Pharmaceutical Company. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: MF YK HY. Performed the experiments: MF. Analyzed the data: MF. Contributed reagents/materials/analysis tools: MF. Wrote the paper: MF.

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