About the Authors

Franziska Zeyer

Contributed equally to this work with: Franziska Zeyer, Benedikt Mothes

Affiliation Department of Pediatrics I - Pediatric Infectiology and Immunology - Translational Genomics and Gene Therapy, University of Tübingen, Tübingen, Germany

Benedikt Mothes

Contributed equally to this work with: Franziska Zeyer, Benedikt Mothes

Affiliation Department of Pharmacology and Experimental Therapy and ICePhA, University of Tübingen, Tübingen, Germany

Clara Will

Affiliation Department of Pediatrics I - Pediatric Infectiology and Immunology - Translational Genomics and Gene Therapy, University of Tübingen, Tübingen, Germany

Melanie Carevic

Affiliation Department of Pediatrics I - Pediatric Infectiology and Immunology - Translational Genomics and Gene Therapy, University of Tübingen, Tübingen, Germany

Jennifer Rottenberger

Affiliation Department of Pediatrics I - Pediatric Infectiology and Immunology - Translational Genomics and Gene Therapy, University of Tübingen, Tübingen, Germany

Bernd Nürnberg

Affiliation Department of Pharmacology and Experimental Therapy and ICePhA, University of Tübingen, Tübingen, Germany

Dominik Hartl

Affiliation Department of Pediatrics I - Pediatric Infectiology and Immunology - Translational Genomics and Gene Therapy, University of Tübingen, Tübingen, Germany

Rupert Handgretinger

Affiliation Department of Pediatrics I - Pediatric Infectiology and Immunology - Translational Genomics and Gene Therapy, University of Tübingen, Tübingen, Germany

Sandra Beer-Hammer

Affiliation Department of Pharmacology and Experimental Therapy and ICePhA, University of Tübingen, Tübingen, Germany

Michael S. D. Kormann

michael.kormann@med.uni-tuebingen.de

Affiliation Department of Pediatrics I - Pediatric Infectiology and Immunology - Translational Genomics and Gene Therapy, University of Tübingen, Tübingen, Germany

Competing Interests

Michael Kormann is listed as co-inventor on a patent application related to modified mRNA licensed to the biopharmaceutical company Ethris GmbH ("RNA with a combination of unmodified and modified nucleotides for protein expression", DE 10 2009 035 507.3; DE 10 2009 050 308.0; PCT/EP2010/004681). This does not alter the authors’ adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: FZ BM SBH MSDK. Performed the experiments: FZ BM CW MC JR. Analyzed the data: FZ BM CW. Contributed reagents/materials/analysis tools: BN RH DH SBH MSDK. Wrote the paper: FZ BM BN DH SBH MSDK.