About the Authors

Juhana Rautiola

Contributed equally to this work with: Juhana Rautiola, Anita Lampinen

Affiliation Comprehensive Cancer Center, Helsinki University Hospital, P.O.B. 180, 00029 HUS, Finland and University of Helsinki, Finland

Anita Lampinen

Contributed equally to this work with: Juhana Rautiola, Anita Lampinen

Affiliation Translational Cancer Biology Program, Research Programs Unit, and Department of Virology, Haartman Institute, Biomedicum Helsinki, Haartmaninkatu 8, P.O.B. 63, FI-00014, University of Helsinki, Finland

Tuomas Mirtti

Affiliations Institute for Molecular Medicine Finland, Haartmaninkatu 8, P.O.B. 63, FI-00014, University of Helsinki, Finland, Pathology, Research Programs Unit and HUSLAB, University of Helsinki and Helsinki University Hospital, P.O.B. 400, FI-00029, HUS, Helsinki, Finland

Ari Ristimäki

Affiliation Pathology, Research Programs Unit and HUSLAB, University of Helsinki and Helsinki University Hospital, P.O.B. 400, FI-00029, HUS, Helsinki, Finland

Heikki Joensuu

Affiliation Comprehensive Cancer Center, Helsinki University Hospital, P.O.B. 180, 00029 HUS, Finland and University of Helsinki, Finland

Petri Bono

Affiliation Comprehensive Cancer Center, Helsinki University Hospital, P.O.B. 180, 00029 HUS, Finland and University of Helsinki, Finland

Pipsa Saharinen

Pipsa.Saharinen@Helsinki.fi

Affiliations Translational Cancer Biology Program, Research Programs Unit, and Department of Virology, Haartman Institute, Biomedicum Helsinki, Haartmaninkatu 8, P.O.B. 63, FI-00014, University of Helsinki, Finland, Wihuri Research Institute, Biomedicum Helsinki, Haartmaninkatu 8, FI-00290, Helsinki, Finland

Competing Interests

PB has received honoratia from Novartis, Pfizer, Bms, Msd, and Orion Pharma, and research funding from Novartis.

Author Contributions

Conceived and designed the experiments: PS PB. Performed the experiments: JR AL. Analyzed the data: JR AL TM AR PB PS. Contributed reagents/materials/analysis tools: AR PS PB. Wrote the paper: JR AL TM AR PB HJ PS.