About the Authors

Jonas Tydén

jonas.tyden@regionjh.se

Affiliations Department of Anaesthesiology and Intensive Care, Östersund Hospital, Östersund, Sweden, Department of Surgical and Perioperative Sciences, Anaesthesiology and Intensive Care, Umeå University, Umeå, Sweden

Heiko Herwald

Affiliation Department of Cell and Molecular Biology, Lund University, Lund, Sweden

Folke Sjöberg

Affiliations Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linköping University, Linköping, Sweden, The Burn Center, Department of Hand, Plastic Surgery and Intensive Care, Linköping County Council, Linköping, Sweden

Joakim Johansson

Affiliations Department of Anaesthesiology and Intensive Care, Östersund Hospital, Östersund, Sweden, Department of Surgical and Perioperative Sciences, Anaesthesiology and Intensive Care, Umeå University, Umeå, Sweden

Competing Interests

The company Hansa Medical has filed a patent for HBP as a diagnostic tool in sepsis. Heiko Herwald is listed as one of the inventors. The other authors have declared that they have no competing interests. This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: JT HH FS JJ. Performed the experiments: JT HH JJ. Analyzed the data: JT FS JJ. Contributed reagents/materials/analysis tools: HH. Wrote the paper: JT HH FS JJ.