About the Authors

Heiner C. Bucher

heiner.bucher@usb.ch

Affiliation Basel Institute for Clinical Epidemiology & Biostatistics, Department of Clinical Research, University Hospital Basel, Basel, Switzerland

Rita Achermann

Affiliation Basel Institute for Clinical Epidemiology & Biostatistics, Department of Clinical Research, University Hospital Basel, Basel, Switzerland

Nadja Stohler

Affiliations Institute for Clinical Pharmacy and Epidemiology, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland, Hospital Pharmacy, University Hospital Basel, Basel, Switzerland

Christoph R. Meier

Affiliations Institute for Clinical Pharmacy and Epidemiology, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland, Hospital Pharmacy, University Hospital Basel, Basel, Switzerland

Competing Interests

The study was financed by Santésuisse (the trustee of Swiss health insurers) and the Swiss Medical Association (FMH). This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: HCB RA NS CRM. Analyzed the data: RA. Contributed reagents/materials/analysis tools: HCB RA NS CRM. Wrote the paper: HCB RA NS CRM.