About the Authors

Chern-En Chiang

cechiang@vghtpe.gov.tw

Affiliation General Clinical Research Center and Division of Cardiology, Taipei Veterans General Hospital, National Yang-Ming University, Taipei, Taiwan

Lisa Naditch-Brûlé

Affiliation Sanofi, Paris, France

Sandrine Brette

Affiliation Lincoln, Boulogne-Billancourt, France

José Silva-Cardoso

Affiliation Department of Cardiology, Porto Medical School, Hospital São João, Porto, Portugal

Habib Gamra

Affiliation University of Monastir and Cardiology A Department, FattoumaBourguiba University Hospital, Monastir, Tunisia–LR12SP16 Cardiothrombosis

Jan Murin

Affiliation Department of Internal Medicine and Cardiology, Comenius University, Bratislava, Slovakia

Oleg J. Zharinov

Affiliation Functional Diagnostics Department, National Medical Academy of Postgraduate Education, Kyiv, Ukraine

Philippe Gabriel Steg

Affiliation INSERM U-1148, Paris, France; Université Paris-Diderot, Paris, France; Assistance Publique–Hôpitaux de Paris, Hôpital Bichat, DHU FIRE, Paris, France; and NHLI, ICMS, Imperial College, Royal Brompton Hospital, London, United Kingdom

Competing Interests

CEC has received honoraria for lectures from AstraZeneca, Merck Sharp & Dohme, Novartis, Pfizer, Sanofi, Daiichi-Sankyo, Bayer, Boehringer Ingelheim, Roche, Servier, Tanabe and Takeda. LNB is an employee of Sanofi and has shares. SB is an employee of Lincoln, under contract with Sanofi for statistical analyses. JSC has consulted and received speaker fees for Abbott, AstraZeneca Pharmaceuticals, Menarini, Merck, Merck Sharp & Dohme, Novartis, Pfizer and Sanofi. HG has received consultancy and lecturing fees/honoraria from Sanofi, Novartis, Astra Zeneca, Boston Scientific and Boehringer-Ingelheim. JM has received honoraria for lectures from Gedeon Richter, Novartis, Pfizer, Roche diagnostics, Servier and Takeda, and consultancy fees from AstraZeneca, Boehringer Ingelheim and Sanofi. OZ has received lecturing fees from Sanofi and Boehringer-Ingelheim. PGS has received research grants from Sanofi and Servier; consultancy fees/honoraria from Amgen, AstraZeneca, Bayer, Boehringer-Ingelheim, Bristol-Myers Squibb, Daiichi-Sankyo/Eli Lilly Alliance, GlaxoSmithKline, Medtronic, Merck Sharpe & Dohme, Novartis, Pfizer, Roche, Sanofi, Servier, The Medicines Company and Vivus, and has equity ownership in Aterovax. LNB is an employee of Sanofi and has shares. SB is an employee of Lincoln, under contract with Sanofi for statistical analyses. This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: CEC LNB SB JSC HG JM OJZ PGS. Performed the experiments: CEC LNB SB JSC HG JM OJZ PGS. Analyzed the data: CEC LNB SB JSC HG JM OJZ PGS. Wrote the paper: CEC LNB SB JSC HG JM OJZ PGS.