Superresolution and Fluorescence Dynamics Evidence Reveal That Intact Liposomes Do Not Cross the Human Skin Barrier

Jes Dreier; Jens A. Sørensen; Jonathan R. Brewer

doi:10.1371/journal.pone.0146514

Loading metrics

Open Access

Peer-reviewed

Research Article

Superresolution and Fluorescence Dynamics Evidence Reveal That Intact Liposomes Do Not Cross the Human Skin Barrier

Jes Dreier,

Affiliation Advanced bioimaging group/MEMPHYS Center for membrane biophysics, Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark
⨯
Jens A. Sørensen,

Affiliation Department of reconstructive surgery, Odense University Hospital, Odense, Denmark
⨯
Jonathan R. Brewer

* E-mail: brewer@bmb.sdu.dk

Affiliation Advanced bioimaging group/MEMPHYS Center for membrane biophysics, Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark
⨯

Superresolution and Fluorescence Dynamics Evidence Reveal That Intact Liposomes Do Not Cross the Human Skin Barrier

Jes Dreier,
Jens A. Sørensen,
Jonathan R. Brewer

Published: January 11, 2016
https://doi.org/10.1371/journal.pone.0146514

About the Authors

Jes Dreier

Affiliation Advanced bioimaging group/MEMPHYS Center for membrane biophysics, Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark

Jens A. Sørensen

Affiliation Department of reconstructive surgery, Odense University Hospital, Odense, Denmark

Jonathan R. Brewer

* E-mail: brewer@bmb.sdu.dk

Affiliation Advanced bioimaging group/MEMPHYS Center for membrane biophysics, Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JRB. Performed the experiments: JRB JD. Analyzed the data: JRB JD. Contributed reagents/materials/analysis tools: JRB JAS. Wrote the paper: JRB JD JAS.

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Vesicles
Is the Subject Area "Vesicles" applicable to this article?

Thanks for your feedback.
Liposomes
Is the Subject Area "Liposomes" applicable to this article?

Thanks for your feedback.
Lipids
Is the Subject Area "Lipids" applicable to this article?

Thanks for your feedback.
Skin
Is the Subject Area "Skin" applicable to this article?

Thanks for your feedback.
Transdermal drug delivery
Is the Subject Area "Transdermal drug delivery" applicable to this article?

Thanks for your feedback.
Fluorescence imaging
Is the Subject Area "Fluorescence imaging" applicable to this article?

Thanks for your feedback.
Iontophoresis
Is the Subject Area "Iontophoresis" applicable to this article?

Thanks for your feedback.
Lipid structure
Is the Subject Area "Lipid structure" applicable to this article?

Thanks for your feedback.