About the Authors
- Enrico Munari
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Affiliation Department of Pathology, Johns Hopkins University, Baltimore, Maryland, 21231, United States of America
- Alcides Chaux
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Affiliations Department of Pathology, Johns Hopkins University, Baltimore, Maryland, 21231, United States of America, Department of Scientific Research, Norte University; Centro para el Desarrollo de la Investigación Científica (CEDIC) Asunción, Asunción, Paraguay
- Ajay M. Vaghasia
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Affiliation Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland, 21231, United States of America
- Diana Taheri
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Affiliations Department of Pathology, Johns Hopkins University, Baltimore, Maryland, 21231, United States of America, Department of Pathology, Isfahan University of Medical Sciences, Isfahan Kidney Diseases Research Center, Isfahan, Iran
- Sarah Karram
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Affiliation Department of Pathology, Johns Hopkins University, Baltimore, Maryland, 21231, United States of America
- Stephania M. Bezerra
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Affiliation Department of Pathology, Johns Hopkins University, Baltimore, Maryland, 21231, United States of America
- Nilda Gonzalez Roibon
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Affiliation Department of Pathology, Johns Hopkins University, Baltimore, Maryland, 21231, United States of America
- William G. Nelson
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Affiliations Department of Pathology, Johns Hopkins University, Baltimore, Maryland, 21231, United States of America, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland, 21231, United States of America, Brady Urological Institute, Johns Hopkins University, Baltimore, Maryland, 21231, United States of America
- Srinivasan Yegnasubramanian
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Affiliation Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland, 21231, United States of America
- George J. Netto
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* E-mail: michael.c.haffner@gmail.com (MCH); gnetto1@jhmi.edu (GJN)
Affiliations Department of Pathology, Johns Hopkins University, Baltimore, Maryland, 21231, United States of America, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland, 21231, United States of America, Brady Urological Institute, Johns Hopkins University, Baltimore, Maryland, 21231, United States of America
- Michael C. Haffner
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* E-mail: michael.c.haffner@gmail.com (MCH); gnetto1@jhmi.edu (GJN)
Affiliations Department of Pathology, Johns Hopkins University, Baltimore, Maryland, 21231, United States of America, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland, 21231, United States of America
Competing Interests
MCH, WGN, SY and the Johns Hopkins University (JHU) have a provisional patent relating to 5hmC detection in tumors (Patent pending, “5-HYDROXYMETHYLCYTOSINE IN HUMAN CANCER”, United States Patent Application number: 13/956,879). This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: MCH GJN EM. Performed the experiments: MCH EM AV SK SB NGR. Analyzed the data: MCH AC EM DT SK SY WGN GJN. Contributed reagents/materials/analysis tools: AC DT. Wrote the paper: MCH EM SY GJN.