About the Authors

Nicole Egli

Affiliation Autoimmune, Transplantation, and Inflammatory Diseases Area, Novartis Institutes for Biomedical Research, Basel, Switzerland

Alexandra Zajonz

Affiliation Autoimmune, Transplantation, and Inflammatory Diseases Area, Novartis Institutes for Biomedical Research, Basel, Switzerland

Matthew T. Burger

Affiliation Global Discovery Chemistry, Novartis Institutes for Biomedical Research, Cambridge, MA, United States of America

Tamas Schweighoffer

tamas.schweighoffer@novartis.com

Affiliation Autoimmune, Transplantation, and Inflammatory Diseases Area, Novartis Institutes for Biomedical Research, Basel, Switzerland

Competing Interests

The authors are employees of Novartis and declare no other competing interest. The commercial affiliation does not alter the authors' adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: NE TS. Performed the experiments: NE AZ MTB TS. Analyzed the data: NE TS. Contributed reagents/materials/analysis tools: NE MTB AZ. Wrote the paper: NE TS.