Conserved Molecular Underpinnings and Characterization of a Role for Caveolin-1 in the Tumor Microenvironment of Mature T-Cell Lymphomas

Tyler A. Herek; Timothy D. Shew; Heather N. Spurgin; Christine E. Cutucache

doi:10.1371/journal.pone.0142682

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Open Access

Peer-reviewed

Research Article

Conserved Molecular Underpinnings and Characterization of a Role for Caveolin-1 in the Tumor Microenvironment of Mature T-Cell Lymphomas

Tyler A. Herek,

Affiliation Department of Biology, University of Nebraska at Omaha, Omaha, Nebraska, United States of America
⨯
Timothy D. Shew,

Affiliation Department of Biology, University of Nebraska at Omaha, Omaha, Nebraska, United States of America
⨯
Heather N. Spurgin,

Affiliation Department of Biology, University of Nebraska at Omaha, Omaha, Nebraska, United States of America
⨯
Christine E. Cutucache

* E-mail: ccutucache@unomaha.edu

Affiliation Department of Biology, University of Nebraska at Omaha, Omaha, Nebraska, United States of America
⨯

Conserved Molecular Underpinnings and Characterization of a Role for Caveolin-1 in the Tumor Microenvironment of Mature T-Cell Lymphomas

Tyler A. Herek,
Timothy D. Shew,
Heather N. Spurgin,
Christine E. Cutucache

Published: November 13, 2015
https://doi.org/10.1371/journal.pone.0142682

About the Authors

Tyler A. Herek

Affiliation Department of Biology, University of Nebraska at Omaha, Omaha, Nebraska, United States of America

Timothy D. Shew

Affiliation Department of Biology, University of Nebraska at Omaha, Omaha, Nebraska, United States of America

Heather N. Spurgin

Affiliation Department of Biology, University of Nebraska at Omaha, Omaha, Nebraska, United States of America

Christine E. Cutucache

* E-mail: ccutucache@unomaha.edu

Affiliation Department of Biology, University of Nebraska at Omaha, Omaha, Nebraska, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: TAH CEC. Performed the experiments: TAH. Analyzed the data: TAH TDS HNS CEC. Wrote the paper: TAH TDS HNS CEC.

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T cells
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Lymphoma
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Protein interaction networks
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Gene expression
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Hematologic cancers and related disorders
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Negative staining
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Serum proteins
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Malignant tumors
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