About the Authors

Ana Maria Fernandez-Pujals

Contributed equally to this work with: Ana Maria Fernandez-Pujals, Mark James Adams, Donald J. MacIntyre

A.Fernandez-2@sms.ed.ac.uk

Affiliation Division of Psychiatry, University of Edinburgh, Edinburgh, United Kingdom

Mark James Adams

Contributed equally to this work with: Ana Maria Fernandez-Pujals, Mark James Adams, Donald J. MacIntyre

Affiliation Division of Psychiatry, University of Edinburgh, Edinburgh, United Kingdom

Pippa Thomson

Affiliation Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom

Andrew G. McKechanie

Affiliation The Patrick Wild Centre, University of Edinburgh, Edinburgh, United Kingdom

Douglas H. R. Blackwood

Affiliation Division of Psychiatry, University of Edinburgh, Edinburgh, United Kingdom

Blair H. Smith

Affiliation Division of Population Health Science, University of Dundee, Dundee, United Kingdom

Anna F. Dominiczak

Affiliation College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom

Andrew D. Morris

Affiliation Usher Institute of Population Health Sciences and Informatics University of Edinburgh, Bioquarter, Edinburgh, United Kingdom

Keith Matthews

Affiliation Division of Neuroscience, University of Dundee, Dundee, United Kingdom

Archie Campbell

Affiliation Generation Scotland, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom

Pamela Linksted

Affiliation Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom

Chris S. Haley

Affiliation MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom

Ian J. Deary

Affiliation Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, University of Edinburgh, Edinburgh, United Kingdom

David J. Porteous

Affiliation Generation Scotland, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom

Donald J. MacIntyre

Contributed equally to this work with: Ana Maria Fernandez-Pujals, Mark James Adams, Donald J. MacIntyre

Affiliation Division of Psychiatry, University of Edinburgh, Edinburgh, United Kingdom

Andrew M. McIntosh

Affiliations Division of Psychiatry, University of Edinburgh, Edinburgh, United Kingdom, Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, University of Edinburgh, Edinburgh, United Kingdom

Competing Interests

AMM has previously received grant support from Pfizer, Lilly and Janssen. These studies are not connected to the current investigation. This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: AMM DJM DJP BHS PL IJD AC KM ADM AFD. Performed the experiments: AMM DJM IJD AGM. Analyzed the data: AMFP MJA DJM. Contributed reagents/materials/analysis tools: CSH PT DHRB. Wrote the paper: AMFP MJA DJM AMM.