About the Authors

Kimihiko Murase

Affiliation Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan

Yasuharu Tabara

Affiliation Center for Genomic Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan

Hiromu Ito

Affiliation Department of Orthopedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan

Masahiko Kobayashi

Affiliation Department of Orthopedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan

Yoshimitsu Takahashi

Affiliation Department of Health Informatics, Kyoto University School of Public Health, Kyoto University, Kyoto, Japan

Kazuya Setoh

Affiliation Center for Genomic Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan

Takahisa Kawaguchi

Affiliation Center for Genomic Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan

Shigeo Muro

Affiliation Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan

Hiroshi Kadotani

Affiliation Department of Psychiatry, Shiga University of Medical Science, Shiga, Japan

Shinji Kosugi

Affiliation Department of Medical Ethics and Medical Genetics, Kyoto University School of Public Health, Kyoto, Japan

Akihiro Sekine

Affiliation Medical Research Support Center, Graduate School of Medicine, Kyoto University, Kyoto, Japan

Ryo Yamada

Affiliation Center for Genomic Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan

Takeo Nakayama

Affiliation Department of Health Informatics, Kyoto University School of Public Health, Kyoto University, Kyoto, Japan

Michiaki Mishima

Affiliation Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan

Shuichi Matsuda

Affiliation Department of Orthopedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan

Fumihiko Matsuda

Affiliation Center for Genomic Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan

Kazuo Chin

chink@kuhp.kyoto-u.ac.jp

Affiliation Department of Respiratory Care and Sleep Control Medicine, Graduate school of medicine, Kyoto University, Kyoto, Japan

Competing Interests

Kazuo Chin declares that the Department of Respiratory Care and Sleep Control Medicine is funded by endowments from Philips-Respironics, Teijin Pharma, Fukuda Denshi and Fukuda Life-tech Kansai to Kyoto University. Hiroshi Kadotani reports that his laboratory is supported by donation from Philips Respironics to Shiga university of Medical Science and that he is a member of the Advisory Board for MSD and Sleepwell; doing collaboration work with Teijin and NPO 0-degree club. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: HI MK Y. Takahashi S. Muro HK SK AS RY TN MM S. Matsuda FM. Performed the experiments: HI MK Y. Takahashi S. Muro HK SK AS RY TN MM FM. Analyzed the data: KM Y. Tabara KS TK KC. Contributed reagents/materials/analysis tools: KM Y. Tabara KS TK RY S. Matsuda KC. Wrote the paper: KM Y. Tabara RY S. Matsuda KC.