About the Authors
- Jo Ishizawa
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Affiliation Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
- Kensuke Kojima
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Affiliations Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America, Hematology, Respiratory Medicine and Oncology, Department of Medicine, Saga University, Saga, Japan
- Teresa McQueen
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Affiliation Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
- Vivian Ruvolo
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Affiliation Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
- Dhruv Chachad
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Affiliation Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
- Graciela M. Nogueras-Gonzalez
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Affiliation Department of Biostatistics, Division of Quantitative Sciences, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
- Xuelin Huang
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Affiliation Department of Biostatistics, Division of Quantitative Sciences, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
- William E. Pierceall
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Affiliation Eutropics Pharmaceuticals, Cambridge, Massachusetts, United States of America
- E. J. Dettman
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Affiliation Eutropics Pharmaceuticals, Cambridge, Massachusetts, United States of America
- Michael H. Cardone
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Affiliation Eutropics Pharmaceuticals, Cambridge, Massachusetts, United States of America
- Sharon Shacham
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Affiliation Karyopharm Therapeutics, Boston, Massachusetts, United States of America
- Marina Konopleva
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Affiliation Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
- Michael Andreeff
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* E-mail: mandreef@mdanderson.org
Affiliation Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
Competing Interests
WEP, EJD and MHC are employees of Eutropics; SS and MK are employees of Karyopharm. MA has research support from Karyopharm and is a member of the SAB of Eutropics. This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: JI VR WEP MHC KK MA. Performed the experiments: JI DC WEP. Analyzed the data: JI VR WEP MHC GMN-G XH KK MA. Contributed reagents/materials/analysis tools: WEP MHC SS VR TM. Wrote the paper: JI WEP MK MHC EJD MA.