About the Authors

Lei Xu

Affiliations Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom, Department of Urology, Zhongshan Hospital, Fudan University, Shanghai, China

Xueying Mao

Affiliation Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom

Ahmet Imrali

Affiliation Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom

Ferrial Syed

Affiliation Department of Medical Oncology, Barts Health NHS, London, United Kingdom

Katherine Mutsvangwa

Affiliations Department of Medical Oncology, Barts Health NHS, London, United Kingdom, Centre for Experimental Medicine, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom

Daniel Berney

Affiliation Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom

Paul Cathcart

Affiliations Centre for Experimental Medicine, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom, Department of Urology, University College Hospital NHS, London, United Kingdom

John Hines

Affiliation Department of Urology, Barts Health NHS, London, United Kingdom

Jonathan Shamash

Affiliations Department of Medical Oncology, Barts Health NHS, London, United Kingdom, Centre for Experimental Medicine, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom

Yong-Jie Lu

y.j.lu@qmul.ac.uk

Affiliation Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom

Competing Interests

The authors have the following interests. This study was partially supported by ANGLE PLC, who owns the Parsortix system. Most of the work using the IsoFlux system was done on a demonstration machine provided by Fluxion Biosciences. The study was planned and conducted and the data are presented independently of both companies. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: LX XM JS YJL. Performed the experiments: LX XM AI. Analyzed the data: LX XM YJL. Contributed reagents/materials/analysis tools: LX FS KM DB PC JH JS. Wrote the paper: LX XM YJL.