About the Authors

Laura K. Erdman

Affiliation Sandra Rotman Centre for Global Health, University Health Network-Toronto General Hospital, Department of Medicine, University of Toronto, Toronto, Ontario, Canada

Valérie D’Acremont

Affiliations Swiss Tropical and Public Health Institute, University of Basel, Basel, Switzerland, Department of Ambulatory Care and Community Medicine, University of Lausanne, Lausanne, Switzerland

Kyla Hayford

Affiliation Sandra Rotman Centre for Global Health, University Health Network-Toronto General Hospital, Department of Medicine, University of Toronto, Toronto, Ontario, Canada

Nimerta Rajwans

† Deceased.

Affiliation Sandra Rotman Centre for Global Health, University Health Network-Toronto General Hospital, Department of Medicine, University of Toronto, Toronto, Ontario, Canada

Mary Kilowoko

Affiliation Amana Regional Referral Hospital, Dar es Salaam, United Republic of Tanzania

Esther Kyungu

Affiliation St-Francis Hospital, Ifakara, United Republic of Tanzania

Philipina Hongoa

Affiliation St-Francis Hospital, Ifakara, United Republic of Tanzania

Leonor Alamo

Affiliation Department of Radiology, University Hospital of Lausanne (CHUV), Lausanne, Switzerland

David L. Streiner

Affiliation Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada

Blaise Genton

Affiliations Swiss Tropical and Public Health Institute, University of Basel, Basel, Switzerland, Department of Ambulatory Care and Community Medicine, University of Lausanne, Lausanne, Switzerland, Infectious Disease Service, University Hospital, Lausanne, Switzerland

Kevin C. Kain

kevin.kain@uhn.ca

Affiliation Sandra Rotman Centre for Global Health, University Health Network-Toronto General Hospital, Department of Medicine, University of Toronto, Toronto, Ontario, Canada

Competing Interests

The authors have read the journal's policy and have the following competing interests: LKE and KCK are named inventors on a patent owned by the University Health Network, entitled “Biomarkers for early determination of a critical or life threatening response to illness and monitoring response to treatment thereof” (International publication number WO2013/127000). There are no other patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: LKE VD BG KCK. Performed the experiments: LKE VD NR MK EK PH. Analyzed the data: LKE VD KH NR LA DLS. Wrote the paper: LKE VD KH NR MK EK PH LA DLS BG KCK.