About the Authors

Siddharth Jhunjhunwala

Affiliations David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, United States of America, Department of Anesthesiology, Boston Children’s Hospital, Boston, Massachusetts, 02115, United States of America

Stephanie Aresta-DaSilva

Affiliations David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, United States of America, Department of Anesthesiology, Boston Children’s Hospital, Boston, Massachusetts, 02115, United States of America

Katherine Tang

Affiliations David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, United States of America, Department of Anesthesiology, Boston Children’s Hospital, Boston, Massachusetts, 02115, United States of America

David Alvarez

Affiliation Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, 02115, United States of America

Matthew J. Webber

Affiliations David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, United States of America, Department of Anesthesiology, Boston Children’s Hospital, Boston, Massachusetts, 02115, United States of America

Benjamin C. Tang

Affiliations David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, United States of America, Department of Anesthesiology, Boston Children’s Hospital, Boston, Massachusetts, 02115, United States of America

Danya M. Lavin

Affiliations David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, United States of America, Department of Anesthesiology, Boston Children’s Hospital, Boston, Massachusetts, 02115, United States of America

Omid Veiseh

Affiliations David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, United States of America, Department of Anesthesiology, Boston Children’s Hospital, Boston, Massachusetts, 02115, United States of America

Joshua C. Doloff

Affiliations David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, United States of America, Department of Anesthesiology, Boston Children’s Hospital, Boston, Massachusetts, 02115, United States of America

Suman Bose

Affiliations David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, United States of America, Department of Anesthesiology, Boston Children’s Hospital, Boston, Massachusetts, 02115, United States of America

Arturo Vegas

Affiliations David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, United States of America, Department of Anesthesiology, Boston Children’s Hospital, Boston, Massachusetts, 02115, United States of America

Minglin Ma

Current Address: Department of Biological and Environmental Engineering, Cornell University, Ithaca, New York, 14853, United States of America

Affiliations David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, United States of America, Department of Anesthesiology, Boston Children’s Hospital, Boston, Massachusetts, 02115, United States of America

Gaurav Sahay

Affiliations David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, United States of America, Department of Anesthesiology, Boston Children’s Hospital, Boston, Massachusetts, 02115, United States of America

Alan Chiu

Affiliations David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, United States of America, Department of Anesthesiology, Boston Children’s Hospital, Boston, Massachusetts, 02115, United States of America

Andrew Bader

Affiliations David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, United States of America, Department of Anesthesiology, Boston Children’s Hospital, Boston, Massachusetts, 02115, United States of America

Erin Langan

Affiliations David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, United States of America, Department of Anesthesiology, Boston Children’s Hospital, Boston, Massachusetts, 02115, United States of America

Sean Siebert

Affiliations David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, United States of America, Department of Anesthesiology, Boston Children’s Hospital, Boston, Massachusetts, 02115, United States of America

Jie Li

Affiliations David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, United States of America, Department of Anesthesiology, Boston Children’s Hospital, Boston, Massachusetts, 02115, United States of America

Dale L. Greiner

Affiliation Department of Molecular Medicine, Diabetes Center of Excellence, University of Massachusetts Medical School, Worcester, Massachusetts, 01605, United States of America

Peter E. Newburger

Affiliations Department of Pediatrics, University of Massachusetts Medical School, Worcester, Massachusetts, 01605, United States of America, Department of Cancer Biology, University of Massachusetts Medical School, Worcester, Massachusetts, 01605, United States of America

Ulrich H. von Andrian

Affiliations Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, 02115, United States of America, The Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, 02139, United States of America

Robert Langer

Affiliations David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, United States of America, Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, United States of America, Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, United States of America, Harvard-MIT Division of Health Science and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, United States of America, Department of Anesthesiology, Boston Children’s Hospital, Boston, Massachusetts, 02115, United States of America

Daniel G. Anderson

dgander@mit.edu

Affiliations David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, United States of America, Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, United States of America, Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, United States of America, Harvard-MIT Division of Health Science and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, United States of America, Department of Anesthesiology, Boston Children’s Hospital, Boston, Massachusetts, 02115, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SJ RL DGA. Performed the experiments: SJ SAD KT DA MJW BCT DML OV JCD SB AV MM GS AC AB EL SS JL. Analyzed the data: SJ DLG PEN RL DGA. Contributed reagents/materials/analysis tools: DA UvA. Wrote the paper: SJ DA DLG PEN UHvA RL DGA.