About the Authors

Charles M. Strom

charles.m.strom@questdiagnostics.com

Affiliation Department of Genetics, Quest Diagnostics Nichols Institute, San Juan Capistrano, CA, United States of America

Steven Rivera

Affiliation Department of Genetics, Quest Diagnostics Nichols Institute, San Juan Capistrano, CA, United States of America

Christopher Elzinga

Affiliation Athena / Quest Diagnostics, Marlborough, MA, United States of America

Taraneh Angeloni

Affiliation Department of Genetics, Quest Diagnostics Nichols Institute, San Juan Capistrano, CA, United States of America

Sun Hee Rosenthal

Affiliation Department of Genetics, Quest Diagnostics Nichols Institute, San Juan Capistrano, CA, United States of America

Dana Goos-Root

Affiliation Department of Genetics, Quest Diagnostics Nichols Institute, San Juan Capistrano, CA, United States of America

Martin Siaw

Affiliation Department of Genetics, Quest Diagnostics Nichols Institute, San Juan Capistrano, CA, United States of America

Jamie Platt

Affiliation Department of Genetics, Quest Diagnostics Nichols Institute, San Juan Capistrano, CA, United States of America

Cory Braastadt

Affiliation Athena / Quest Diagnostics, Marlborough, MA, United States of America

Linda Cheng

Affiliation Department of Genetics, Quest Diagnostics Nichols Institute, San Juan Capistrano, CA, United States of America

David Ross

Affiliation Celera / Quest Diagnostics, Alameda, CA, United States of America

Weimin Sun

Affiliation Department of Genetics, Quest Diagnostics Nichols Institute, San Juan Capistrano, CA, United States of America

Competing Interests

Charles M Strom, Steven Rivera, Christopher Elzinga, Taraneh Angeloni, Sun Hee Rosenthal, Dana Goos-Root, Martin Siaw, Jamie Platt, Linda Cheng, and Weimin Sun are employees of Quest Diagnostics Nichols Institute. Cory Braastadt is an employee of Athena/Quest Diagnostics. David Ross is an employee of Celera/Quest Diagnostics. Quest Diagnostics provides BRCA testing services. This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: CMS SR CE TA SHR DG MS JP LC WS CB DR. Performed the experiments: CMS SR CE TA SHR DG MS JP LC WS CB DR. Analyzed the data: CMS SR CE TA SHR DG MS JP LC WS CB DR. Contributed reagents/materials/analysis tools: CMS SR CE TA SHR DG MS JP LC WS CB DR. Wrote the paper: CMS SR CE TA SHR DG MS JP LC WS CB DR.