About the Authors

Paulina Kasperkiewicz

Affiliations Division of Bioorganic Chemistry, Faculty of Chemistry, Wroclaw University of Technology, Wyb. Wyspianskiego 27, Wroclaw 50–370, Poland, Program in Cell Death and Survival Networks, Sanford-Burnham Medical Research Institute, 10901 North Torrey Pines Road, La Jolla, CA 92024, United States of America

Marcin Poreba

Affiliation Division of Bioorganic Chemistry, Faculty of Chemistry, Wroclaw University of Technology, Wyb. Wyspianskiego 27, Wroclaw 50–370, Poland

Scott J. Snipas

Affiliation Program in Cell Death and Survival Networks, Sanford-Burnham Medical Research Institute, 10901 North Torrey Pines Road, La Jolla, CA 92024, United States of America

S. Jack Lin

Affiliation Dept. of Early Discovery Biochemistry, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, United States of America

Daniel Kirchhofer

Affiliation Dept. of Early Discovery Biochemistry, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, United States of America

Guy S. Salvesen

marcin.drag@pwr.edu.pl (MD); gsalvesen@sanfordburnham.org (GS)

Affiliation Program in Cell Death and Survival Networks, Sanford-Burnham Medical Research Institute, 10901 North Torrey Pines Road, La Jolla, CA 92024, United States of America

Marcin Drag

marcin.drag@pwr.edu.pl (MD); gsalvesen@sanfordburnham.org (GS)

Affiliation Division of Bioorganic Chemistry, Faculty of Chemistry, Wroclaw University of Technology, Wyb. Wyspianskiego 27, Wroclaw 50–370, Poland

Competing Interests

The authors have the following interests: Co-authors S. Jack Lin and Daniel Kirchhofer are employed by Genentech Inc. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials as detailed online in our guide for authors http://www.PLOSone.org/static/editorial.action#competing.

Author Contributions

Conceived and designed the experiments: PK MP SJS SJL DK GSS MD. Performed the experiments: PK MP SJS SJL. Analyzed the data: PK MP SJS GSS MD. Contributed reagents/materials/analysis tools: SJL DK. Wrote the paper: PK MP SJS SJL DK GSS MD.