About the Authors

Akiko Furutani

Contributed equally to this work with: Akiko Furutani, Yuko Ikeda

Affiliation Laboratory of Physiology and Pharmacology, School of Advanced Science and Engineering, Waseda University, Wakamatsu-cho 2–2, Shinjuku-ku, Tokyo, Japan

Yuko Ikeda

Contributed equally to this work with: Akiko Furutani, Yuko Ikeda

Affiliation Laboratory of Physiology and Pharmacology, School of Advanced Science and Engineering, Waseda University, Wakamatsu-cho 2–2, Shinjuku-ku, Tokyo, Japan

Misa Itokawa

Affiliation Laboratory of Physiology and Pharmacology, School of Advanced Science and Engineering, Waseda University, Wakamatsu-cho 2–2, Shinjuku-ku, Tokyo, Japan

Hiroki Nagahama

Affiliation Laboratory of Physiology and Pharmacology, School of Advanced Science and Engineering, Waseda University, Wakamatsu-cho 2–2, Shinjuku-ku, Tokyo, Japan

Teiji Ohtsu

Affiliation Laboratory of Physiology and Pharmacology, School of Advanced Science and Engineering, Waseda University, Wakamatsu-cho 2–2, Shinjuku-ku, Tokyo, Japan

Naoki Furutani

Affiliation Laboratory of Physiology and Pharmacology, School of Advanced Science and Engineering, Waseda University, Wakamatsu-cho 2–2, Shinjuku-ku, Tokyo, Japan

Mayo Kamagata

Affiliation Laboratory of Physiology and Pharmacology, School of Advanced Science and Engineering, Waseda University, Wakamatsu-cho 2–2, Shinjuku-ku, Tokyo, Japan

Zhi-Hong Yang

Affiliation Central Research Laboratory, Nippon Suisan Kaisha Ltd., Nanakuni 1-32-3, Hachioji, Tokyo, Japan

Akira Hirasawa

Affiliations Department of Genomic Drug Discovery Sciences, Kyoto University, 46–29, Yoshida, Sakyo-ku, Kyoto, Japan, Institute for Integrated Medical Sciences, Tokyo Women’s Medical University, Kawada-cho 8–1, Shinjuku-ku, Tokyo, Japan

Yu Tahara

Affiliation Laboratory of Physiology and Pharmacology, School of Advanced Science and Engineering, Waseda University, Wakamatsu-cho 2–2, Shinjuku-ku, Tokyo, Japan

Shigenobu Shibata

shibatas@waseda.jp

Affiliation Laboratory of Physiology and Pharmacology, School of Advanced Science and Engineering, Waseda University, Wakamatsu-cho 2–2, Shinjuku-ku, Tokyo, Japan

Competing Interests

I have read the journal's policy and the authors of this manuscript have the following competing interests: Zhi-Hong Yang is employed by Nippon Suisan Kaisha Ltd., and helped to examine the fatty acid analysis in the fish oil for this study. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: SS. Performed the experiments: AF YI MI HN TO NF YT MK. Analyzed the data: ZHY. Contributed reagents/materials/analysis tools: AH. Wrote the paper: SS AF YI.