Protein Thermostability Is Owing to Their Preferences to Non-Polar Smaller Volume Amino Acids, Variations in Residual Physico-Chemical Properties and More Salt-Bridges

Anindya Sundar Panja; Bidyut Bandopadhyay; Smarajit Maiti

doi:10.1371/journal.pone.0131495

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Peer-reviewed

Research Article

Protein Thermostability Is Owing to Their Preferences to Non-Polar Smaller Volume Amino Acids, Variations in Residual Physico-Chemical Properties and More Salt-Bridges

Anindya Sundar Panja,

Affiliation Post Graduate Department of Biotechnology, Oriental Institute of Science and Technology, Vidyasagar University, Midnapore, 721102, West Bengal, India
⨯
Bidyut Bandopadhyay,

Affiliation Post Graduate Department of Biotechnology, Oriental Institute of Science and Technology, Vidyasagar University, Midnapore, 721102, West Bengal, India
⨯
Smarajit Maiti

* E-mail: maitism@rediffmail.com

Affiliation Post Graduate Department of Biochemistry and Biotechnology, Cell and Molecular Therapeutics Laboratory, Oriental Institute of Science and Technology, Vidyasagar University, Midnapore, 721102, West Bengal, India
⨯

Protein Thermostability Is Owing to Their Preferences to Non-Polar Smaller Volume Amino Acids, Variations in Residual Physico-Chemical Properties and More Salt-Bridges

Anindya Sundar Panja,
Bidyut Bandopadhyay,
Smarajit Maiti

Published: July 15, 2015
https://doi.org/10.1371/journal.pone.0131495

About the Authors

Anindya Sundar Panja

Affiliation Post Graduate Department of Biotechnology, Oriental Institute of Science and Technology, Vidyasagar University, Midnapore, 721102, West Bengal, India

Bidyut Bandopadhyay

Affiliation Post Graduate Department of Biotechnology, Oriental Institute of Science and Technology, Vidyasagar University, Midnapore, 721102, West Bengal, India

Smarajit Maiti

* E-mail: maitism@rediffmail.com

Affiliation Post Graduate Department of Biochemistry and Biotechnology, Cell and Molecular Therapeutics Laboratory, Oriental Institute of Science and Technology, Vidyasagar University, Midnapore, 721102, West Bengal, India

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: ASP BB SM. Performed the experiments: ASP SM. Analyzed the data: SM BB. Contributed reagents/materials/analysis tools: ASP SM. Wrote the paper: SM.

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Extremophiles
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Salt bridges
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Protein structure
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Phosphorylation
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Amino acid analysis
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Evolutionary adaptation
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Glycine
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Molecular evolution
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