About the Authors

Andrew Wu

Affiliation School of Medicine, Vanderbilt University, Nashville, Tennessee, United States of America

Philip J. Budge

Affiliation Division of Infectious Diseases, Washington University School of Medicine, St. Louis, Missouri, United States of America

John Williams

Affiliations Department of Pediatrics, Vanderbilt University, Nashville, Tennessee, United States of America, Department of Pathology, Microbiology, and Immunology, Vanderbilt University, Nashville, Tennessee, United States of America

Marie R. Griffin

Affiliation Department of Health Policy, Vanderbilt University, Nashville, Tennessee, United States of America

Kathryn M. Edwards

Affiliations Department of Pediatrics, Vanderbilt University, Nashville, Tennessee, United States of America, Vanderbilt Vaccine Research Program, Division of Infectious Diseases, Department of Pediatrics, Vanderbilt University, Nashville, Tennessee, United States of America

Monika Johnson

Affiliation Department of Pediatrics, Vanderbilt University, Nashville, Tennessee, United States of America

Yuwei Zhu

Affiliation Department of Biostatistics, Vanderbilt University, Nashville, Tennessee, United States of America

Stella Hartinger

Affiliations Swiss Tropical and Public Health Institute, Basel, Switzerland, Instituto de Investigación Nutricional, Lima, Peru

Hector Verastegui

Affiliation Instituto de Investigación Nutricional, Lima, Peru

Ana I. Gil

Affiliation Instituto de Investigación Nutricional, Lima, Peru

Claudio F. Lanata

Affiliation Instituto de Investigación Nutricional, Lima, Peru

Carlos G. Grijalva

Carlos.grijalva@vanderbilt.edu

Affiliation Department of Health Policy, Vanderbilt University, Nashville, Tennessee, United States of America

Competing Interests

CGG has served as consultant for GSK and Pfizer. CFL is an advisor to Takeda Vaccines Division. JVW serves on the Scientific Advisory Board of Quidel. MRG has grant funding from MedImmune. KME has received research funding and serves on a Data Safety and Monitoring Board for Novartis. All other authors have no potential competing interests to report. This work was supported by the Vanderbilt University CTSA grant UL1 RR024975 from National Institutes of Health, an investigator initiated research grant from Pfizer (IIR WS1898786(0887X1-4492), http://www.pfizer.com) and grant 02832-9 from the Thrasher Research Fund (www.thrasherresearch.org/default.aspx). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. The funding support does not alter the authors’ adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: JW MG KE MJ SH HV AG CL CG. Performed the experiments: MG KE SH CG. Analyzed the data: AW PB YZ CG. Contributed reagents/materials/analysis tools: JW HV AG CL. Wrote the paper: AW PB JW MG KE YZ HV CL CG.