About the Authors

Yali Qin

Affiliations Department of Biomedical Sciences, Iowa State University, Ames, IA, 50011, United States of America, Center for Advanced Host Defenses, Immunobiotics and Translational Comparative Medicine, Iowa State University, Ames, IA, 50011, United States of America

Saikat Banerjee

Contributed equally to this work with: Saikat Banerjee, Aditi Agrawal

Affiliations Department of Biomedical Sciences, Iowa State University, Ames, IA, 50011, United States of America, Center for Advanced Host Defenses, Immunobiotics and Translational Comparative Medicine, Iowa State University, Ames, IA, 50011, United States of America

Aditi Agrawal

Contributed equally to this work with: Saikat Banerjee, Aditi Agrawal

Affiliations Department of Biomedical Sciences, Iowa State University, Ames, IA, 50011, United States of America, Center for Advanced Host Defenses, Immunobiotics and Translational Comparative Medicine, Iowa State University, Ames, IA, 50011, United States of America

Heliang Shi

Affiliations Department of Biomedical Sciences, Iowa State University, Ames, IA, 50011, United States of America, Center for Advanced Host Defenses, Immunobiotics and Translational Comparative Medicine, Iowa State University, Ames, IA, 50011, United States of America

Marisa Banasik

Affiliations Department of Biomedical Sciences, Iowa State University, Ames, IA, 50011, United States of America, Center for Advanced Host Defenses, Immunobiotics and Translational Comparative Medicine, Iowa State University, Ames, IA, 50011, United States of America

Feng Lin

Affiliations Department of Biomedical Sciences, Iowa State University, Ames, IA, 50011, United States of America, Center for Advanced Host Defenses, Immunobiotics and Translational Comparative Medicine, Iowa State University, Ames, IA, 50011, United States of America

Kari Rohl

Affiliations Department of Biomedical Sciences, Iowa State University, Ames, IA, 50011, United States of America, Center for Advanced Host Defenses, Immunobiotics and Translational Comparative Medicine, Iowa State University, Ames, IA, 50011, United States of America

Celia LaBranche

Affiliation Department of Surgery, Duke University, Durham, NC, 27710, United States of America

David C. Montefiori

Affiliation Department of Surgery, Duke University, Durham, NC, 27710, United States of America

Michael W. Cho

mcho@iastate.edu

Affiliations Department of Biomedical Sciences, Iowa State University, Ames, IA, 50011, United States of America, Center for Advanced Host Defenses, Immunobiotics and Translational Comparative Medicine, Iowa State University, Ames, IA, 50011, United States of America

Competing Interests

The authors have read the journal's policy and the authors of this manuscript have the following competing interests: MWC has an equity interest in NeoVaxSyn Inc., and serves as CEO/President. NeoVaxSyn Inc. did not contribute to this work or the interpretation of the data. This does not alter the authors’ adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: YQ SB AA MWC. Performed the experiments: YQ SB AA HS MB FL KR CL. Analyzed the data: YQ SB AA MB CL DCM MWC. Wrote the paper: YQ SB AA HS MB FL KR CL DCM MWC.