About the Authors

Gerard H. Bode

Affiliation Department of Neuroscience, School for Mental Health and Neuroscience, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, the Netherlands

Karin E. Pickl

Affiliation HEALTH—Institute for Biomedicine and Health Sciences, Joanneum Research Forschungsgesellschaft m.b.H, Graz, Austria

Maria Sanchez-Purrà

Affiliation Grup d'Enginyeria de Materials (GEMAT), Institut Químic de Sarrià, Universitat Ramon Llull, Barcelona, Spain

Berta Albaiges

Affiliation Grup d'Enginyeria de Materials (GEMAT), Institut Químic de Sarrià, Universitat Ramon Llull, Barcelona, Spain

Salvador Borrós

Affiliation Grup d'Enginyeria de Materials (GEMAT), Institut Químic de Sarrià, Universitat Ramon Llull, Barcelona, Spain

Andy J. G. Pötgens

Affiliation AplaGen GmbH, Arnold-Sommerfeld-Ring 2, Baesweiler, Germany

Christoph Schmitz

Affiliation Department of Neuroanatomy, Ludwig-Maximilians-University of Munich, Munich, Germany

Frank M. Sinner

Affiliation Medical University of Graz, Department of Internal Medicine, Division of Endocrinology and Metabolism, Graz, Austria

Mario Losen

Affiliation Department of Neuroscience, School for Mental Health and Neuroscience, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, the Netherlands

Harry W. M. Steinbusch

Affiliation Department of Neuroscience, School for Mental Health and Neuroscience, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, the Netherlands

Hans-Georg Frank

Affiliations AplaGen GmbH, Arnold-Sommerfeld-Ring 2, Baesweiler, Germany, Department of Neuroanatomy, Ludwig-Maximilians-University of Munich, Munich, Germany

Pilar Martinez-Martinez

p.martinez@maastrichtuniversity.nl

Affiliation Department of Neuroscience, School for Mental Health and Neuroscience, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, the Netherlands

European NanoBioPharmaceutics Research Initiative

Membership of the European NanoBioPharmaceutics Research Initiative is listed in the Acknowledgments.

Competing Interests

Although one or more of the authors are employed by a commercial company, AplaGen GmbH, this does not alter the authors' adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: ML FMS AJGP H-GF CS SB PM-M. Performed the experiments: GHB KEP BA MS-P. Analyzed the data: GHB KEP. Contributed reagents/materials/analysis tools: AJGP H-GF CS SB HWMS. Wrote the paper: GHB KEP ML PM-M.