Key Glycolytic Enzyme Activities of Skeletal Muscle Are Decreased under Fed and Fasted States in Mice with Knocked Down Levels of Shc Proteins

Kevork Hagopian; Alexey A. Tomilov; Kyoungmi Kim; Gino A. Cortopassi; Jon J. Ramsey

doi:10.1371/journal.pone.0124204

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Open Access

Peer-reviewed

Research Article

Key Glycolytic Enzyme Activities of Skeletal Muscle Are Decreased under Fed and Fasted States in Mice with Knocked Down Levels of Shc Proteins

Kevork Hagopian ,

* E-mail: khagopian@ucdavis.edu

Affiliation Department of Molecular Biosciences, School of Veterinary Medicine, University of California Davis, Davis, CA 95616, United States of America
⨯
Alexey A. Tomilov,

Affiliation Department of Molecular Biosciences, School of Veterinary Medicine, University of California Davis, Davis, CA 95616, United States of America
⨯
Kyoungmi Kim,

Affiliation Department of Public Health Sciences, University of California Davis, Davis, CA 95616, United States of America
⨯
Gino A. Cortopassi,

Affiliation Department of Molecular Biosciences, School of Veterinary Medicine, University of California Davis, Davis, CA 95616, United States of America
⨯
Jon J. Ramsey

Affiliation Department of Molecular Biosciences, School of Veterinary Medicine, University of California Davis, Davis, CA 95616, United States of America
⨯

Key Glycolytic Enzyme Activities of Skeletal Muscle Are Decreased under Fed and Fasted States in Mice with Knocked Down Levels of Shc Proteins

Kevork Hagopian,
Alexey A. Tomilov,
Kyoungmi Kim,
Gino A. Cortopassi,
Jon J. Ramsey

Published: April 16, 2015
https://doi.org/10.1371/journal.pone.0124204

About the Authors

Kevork Hagopian

* E-mail: khagopian@ucdavis.edu

Affiliation Department of Molecular Biosciences, School of Veterinary Medicine, University of California Davis, Davis, CA 95616, United States of America

Alexey A. Tomilov

Affiliation Department of Molecular Biosciences, School of Veterinary Medicine, University of California Davis, Davis, CA 95616, United States of America

Kyoungmi Kim

Affiliation Department of Public Health Sciences, University of California Davis, Davis, CA 95616, United States of America

Gino A. Cortopassi

Affiliation Department of Molecular Biosciences, School of Veterinary Medicine, University of California Davis, Davis, CA 95616, United States of America

Jon J. Ramsey

Affiliation Department of Molecular Biosciences, School of Veterinary Medicine, University of California Davis, Davis, CA 95616, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: KH AAT. Performed the experiments: KH AAT. Analyzed the data: KH AAT KK. Contributed reagents/materials/analysis tools: GAC JJR. Wrote the paper: KH JJR.

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Skeletal muscles
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Glucose
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Enzyme regulation
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Fatty acids
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Pyruvate
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Glucose metabolism
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Glycolysis
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Mouse models
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