About the Authors

Chih-Hao Chen

chih_hao_chen@yahoo.com (CHC); sulijen@gmail.com (LJS); hclee12345@gmail.com (HCL)

Affiliations Institute of Systems Biology and Bioinformatics, National Central University, Chungli, Taiwan 32001, Cathay Medical Research Institute, Cathay General Hospital, Taipei, Taiwan 10630

Chueh-Lin Hsu

Affiliation Institute of Systems Biology and Bioinformatics, National Central University, Chungli, Taiwan 32001

Shih-Hao Huang

Affiliation Institute of Systems Biology and Bioinformatics, National Central University, Chungli, Taiwan 32001

Shih-Yuan Chen

Affiliation Institute of Systems Biology and Bioinformatics, National Central University, Chungli, Taiwan 32001

Yi-Lin Hung

Affiliation Institute of Bioinformatics and Structural Biology, National Tsing Hua University, Hsinchu, Taiwan 30013

Hsiao-Rong Chen

Affiliation Department of Medicine, Boston University School of Medicine, Boston, MA 02118, United States of America

Yu-Chung Wu

Affiliations Division of Thoracic Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei, Taiwan 11217, School of Medicine, National Yang-Ming University, Taipei, Taiwan 11221

Li-Jen Su

Contributed equally to this work with: Li-Jen Su, H.C. Lee

chih_hao_chen@yahoo.com (CHC); sulijen@gmail.com (LJS); hclee12345@gmail.com (HCL)

Affiliation Institute of Systems Biology and Bioinformatics, National Central University, Chungli, Taiwan 32001

H.C. Lee

Contributed equally to this work with: Li-Jen Su, H.C. Lee

chih_hao_chen@yahoo.com (CHC); sulijen@gmail.com (LJS); hclee12345@gmail.com (HCL)

Affiliations Institute of Systems Biology and Bioinformatics, National Central University, Chungli, Taiwan 32001, National Center for Theoretical Sciences, Hsinchu, Taiwan 30043, Department of Physics, National Central University, Chungli, Taiwan 32001, Center for Dynamical Biomarkers and Translational Medicine, National Central University, Chungli, Taiwan 32001

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: CC. Performed the experiments: CC CH SH SC YH HC. Analyzed the data: CC CH SH SC YH HC. Contributed reagents/materials/analysis tools: CC. Wrote the paper: YW LS HL.