About the Authors

Lara J. Wolfson

LWolfson@its.jnj.com

Affiliation Janssen Pharmaceutica NV, Beerse, Belgium

Anna Walker

Affiliation HERON Commercialization, London, United Kingdom

Robert Hettle

Affiliation HERON Commercialization, London, United Kingdom

Xiaoyan Lu

Affiliation Janssen Pharmaceutica NV, Beerse, Belgium

Chrispin Kambili

Affiliation Janssen Global Services LLC, Raritan, New Jersey, United States of America

Andrew Murungi

Affiliation Janssen (Janssen-Cilag), High Wycombe, United Kingdom

Gerhart Knerer

Affiliation Janssen (Janssen-Cilag), High Wycombe, United Kingdom

Competing Interests

The authors have the following interests: L.J. Wolfson and X. Lu were employed by Janssen Pharmaceutica N.V. at the time of writing this manuscript; C. Kambili was employed by Janssen Global Services LLC; and G. Knerer and A. Murungi were employed by Janssen-Cilag. R. Hettle and A. Walker were commissioned by Janssen Pharmaceutica N.V. to prepare the cost-effectiveness model that this manuscript is based on. Anna Walker and Robert Hettle are employed by HERON™ Commercialization. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: LW AW RH. Performed the experiments: LW AW RH XL. Analyzed the data: LW AW RH CK GK AM. Wrote the paper: LW AW RH CK GK AM. Acquisition of data: LW AW RH XL. Providing critical revision of the manuscript: LW AW RH CK GK AM. Providing final approval of the version to publish: LW AW RH CK GK AM.