About the Authors

Guowei Li

Contributed equally to this work with: Guowei Li, Jonathan D. Adachi

jd.adachi@sympatico.ca (JDA); lig28@mcmaster.ca (GL)

Affiliation Department of Clinical Epidemiology & Biostatistics, McMaster University, Hamilton, Ontario, Canada

Lehana Thabane

Affiliations Department of Clinical Epidemiology & Biostatistics, McMaster University, Hamilton, Ontario, Canada, St. Joseph’s Hospital, McMaster University, Hamilton, Ontario, Canada

George Ioannidis

Affiliation Department of Medicine, McMaster University, Hamilton, Ontario, Canada

Courtney Kennedy

Affiliation Department of Clinical Epidemiology & Biostatistics, McMaster University, Hamilton, Ontario, Canada

Alexandra Papaioannou

Affiliation Department of Medicine, McMaster University, Hamilton, Ontario, Canada

Jonathan D. Adachi

Contributed equally to this work with: Guowei Li, Jonathan D. Adachi

jd.adachi@sympatico.ca (JDA); lig28@mcmaster.ca (GL)

Affiliations St. Joseph’s Hospital, McMaster University, Hamilton, Ontario, Canada, Department of Medicine, McMaster University, Hamilton, Ontario, Canada

Competing Interests

Dr. Jonathan D. Adachi was a consultant and speaker of Sanofi-Aventis. However, this does not alter the authors' adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: GL JDA. Performed the experiments: JDA. Analyzed the data: GL LT JDA. Contributed reagents/materials/analysis tools: GL LT JDA. Wrote the paper: GL LT JDA. Critical revisions of the manuscript: GI CK AP.