About the Authors

Libin Zhan

Affiliations Department of Traditional Chinese Medicine, The Second Affiliated Hospital, Dalian Medical University, Dalian, China, Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan, College (Institute) of Integrative Medicine, Dalian Medical University, Dalian, China

Luping Zheng

Affiliation College (Institute) of Integrative Medicine, Dalian Medical University, Dalian, China

Toru Hosoi

Affiliations Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan, Department of Pharmacotherapy, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan

Yasunobu Okuma

Affiliations Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan, Department of Pharmacology, Faculty of Pharmaceutical Sciences, Chiba Institute of Sciences, Choshi, Japan

Yasuyuki Nomura

nomura_yasuyuki@kurume-u.ac.jp

Affiliations Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan, Department of Pharmacology, Kurume University School of Medicine, Kurume, Fukuoka, Japan

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: TH YO YN. Performed the experiments: L. Zhan. Analyzed the data: L. Zhan. Wrote the paper: L. Zhan L. Zheng.