About the Authors

Georgina C. Morris

Affiliation Centre for Immunology and Infection, Hull York Medical School, University of York, York, United Kingdom

Rebecca C. Wiggins

Affiliation Centre for Immunology and Infection, Hull York Medical School, University of York, York, United Kingdom

Sarah C. Woodhall

Affiliation Centre for Immunology and Infection, Hull York Medical School, University of York, York, United Kingdom

J. Martin Bland

Affiliation Department of Health Sciences, University of York, York, United Kingdom

Carol R. Taylor

Affiliation Hull York Medical School Experimental Medicine Unit, York Teaching Hospitals NHS Foundation Trust, York, United Kingdom

Vicky Jespers

Affiliation Institute of Tropical Medicine, Antwerp, Belgium

Brigitta A. Vcelar

Affiliation Polymun Scientific Immunbiologische Forschung GmbH, Vienna, Austria

Charles J. Lacey

charles.lacey@hyms.ac.uk

Affiliation Centre for Immunology and Infection, Hull York Medical School, University of York, York, United Kingdom

Competing Interests

The authors have the following interests: BAV is an employee responsible for clinical research at Polymun Scientific GmbH (Austria), a company involved in the commercial development of 2F5, 4E10 and 2G12 but holds no equity in that company nor are BAV's responsibilities related to the molecules investigated. We have no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: GCM RCW SCW VJ CJL. Performed the experiments: GCM RCW CRT VJ BAV CJL. Analyzed the data: GCM JMB VJ CJL. Contributed reagents/materials/analysis tools: RCW JMB VJ BAV. Wrote the paper: GCM RCW SCW JMB CRT VJ BAV CJL. Study co-ordination: GCM CRT.