About the Authors

Jun Guo

Affiliation Oncology Division, Research & Development, AbbVie Inc., North Chicago, Illinois, United States of America

Lisa Roberts

Affiliation Oncology Division, Research & Development, AbbVie Inc., North Chicago, Illinois, United States of America

Zhui Chen

Current address: Novartis Institutes for BioMedical Research (China), Shanghai, P.R. China

Affiliation Oncology Division, Research & Development, AbbVie Inc., North Chicago, Illinois, United States of America

Philip J. Merta

Affiliation Oncology Division, Research & Development, AbbVie Inc., North Chicago, Illinois, United States of America

Keith B. Glaser

keith.glaser@abbvie.com

Affiliation Oncology Division, Research & Development, AbbVie Inc., North Chicago, Illinois, United States of America

O. Jameel Shah

Current address: Eurofins Panlabs Inc., Bothell, Washington, United States of America

Affiliation Oncology Division, Research & Development, AbbVie Inc., North Chicago, Illinois, United States of America

Competing Interests

JG, LR, PM, OJS, and KG are employees, former employees, or retirees of Abbott/AbbVie. The design, research, and financial support for this research was provided by AbbVie. AbbVie participated in the interpretation of data, review, and approval of the manuscript. This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: JG OJS. Performed the experiments: JG OJS LR PJM ZC. Analyzed the data: JG OJS. Contributed reagents/materials/analysis tools: JG OJS LR PJM ZC KG. Wrote the paper: OJS JG KG.