About the Authors

Yuichi Shiraishi

Affiliation Laboratory of DNA Information Analysis, Human Genome Center, The Institute of Medical Science, The University of Tokyo, Tokyo, 108-8639, Japan

Akihiro Fujimoto

Affiliations Laboratory for Genome Sequencing Analysis, RIEKN Center for Integrative Medical Sciences, Yokohama, 230-0045, Japan, Laboratory for Medical Science Mathematics, RIEKN Center for Integrative Medical Sciences, Yokohama, 230-0045, Japan

Mayuko Furuta

Affiliation Laboratory for Genome Sequencing Analysis, RIEKN Center for Integrative Medical Sciences, Yokohama, 230-0045, Japan

Hiroko Tanaka

Affiliation Laboratory of Sequence Analysis, Human Genome Center, The Institute of Medical Science, The University of Tokyo, Tokyo, 108-8639, Japan

Ken-ichi Chiba

Affiliation Laboratory of DNA Information Analysis, Human Genome Center, The Institute of Medical Science, The University of Tokyo, Tokyo, 108-8639, Japan

Keith A. Boroevich

Affiliation Laboratory for Medical Science Mathematics, RIEKN Center for Integrative Medical Sciences, Yokohama, 230-0045, Japan

Tetsuo Abe

Affiliation Laboratory for Medical Science Mathematics, RIEKN Center for Integrative Medical Sciences, Yokohama, 230-0045, Japan

Yoshiiku Kawakami

Affiliation Department of Medicine & Molecular Science, Hiroshima University School of Medicine, Hiroshima, 734-8551, Japan

Masaki Ueno

Affiliation Second Department of Surgery, Wakayama Medical University, Wakayama, 641-8510, Japan

Kunihito Gotoh

Affiliation Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, 537-8511, Japan

Shun-ichi Ariizumi

Affiliation Department of Surgery, Institute of Gastroenterology, Tokyo Women's Medical University, Tokyo, 162-8666, Japan

Tetsuo Shibuya

Affiliation Laboratory of Sequence Analysis, Human Genome Center, The Institute of Medical Science, The University of Tokyo, Tokyo, 108-8639, Japan

Kaoru Nakano

Affiliation Laboratory for Genome Sequencing Analysis, RIEKN Center for Integrative Medical Sciences, Yokohama, 230-0045, Japan

Aya Sasaki

Affiliation Laboratory for Genome Sequencing Analysis, RIEKN Center for Integrative Medical Sciences, Yokohama, 230-0045, Japan

Kazuhiro Maejima

Affiliation Laboratory for Genome Sequencing Analysis, RIEKN Center for Integrative Medical Sciences, Yokohama, 230-0045, Japan

Rina Kitada

Affiliation Laboratory for Genome Sequencing Analysis, RIEKN Center for Integrative Medical Sciences, Yokohama, 230-0045, Japan

Shinya Hayami

Affiliation Second Department of Surgery, Wakayama Medical University, Wakayama, 641-8510, Japan

Yoshinobu Shigekawa

Affiliation Second Department of Surgery, Wakayama Medical University, Wakayama, 641-8510, Japan

Shigeru Marubashi

Affiliation Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, 537-8511, Japan

Terumasa Yamada

Affiliation Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, 537-8511, Japan

Michiaki Kubo

Affiliation Laboratory for Genotyping Development, RIEKN Center for Integrative Medical Sciences, Yokohama, 230-0045, Japan

Osamu Ishikawa

Affiliation Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, 537-8511, Japan

Hiroshi Aikata

Affiliation Department of Medicine & Molecular Science, Hiroshima University School of Medicine, Hiroshima, 734-8551, Japan

Koji Arihiro

Affiliation Department of Anatomical Pathology, Hiroshima University School of Medicine, Hiroshima, 734-8551, Japan

Hideki Ohdan

Affiliation Department of Gastroenterological Surgery, Hiroshima University School of Medicine, Hiroshima, 734-8551, Japan

Masakazu Yamamoto

Affiliation Department of Surgery, Institute of Gastroenterology, Tokyo Women's Medical University, Tokyo, 162-8666, Japan

Hiroki Yamaue

Affiliation Second Department of Surgery, Wakayama Medical University, Wakayama, 641-8510, Japan

Kazuaki Chayama

Affiliation Department of Medicine & Molecular Science, Hiroshima University School of Medicine, Hiroshima, 734-8551, Japan

Tatsuhiko Tsunoda

Affiliation Laboratory for Medical Science Mathematics, RIEKN Center for Integrative Medical Sciences, Yokohama, 230-0045, Japan

Satoru Miyano

Affiliations Laboratory of DNA Information Analysis, Human Genome Center, The Institute of Medical Science, The University of Tokyo, Tokyo, 108-8639, Japan, Laboratory of Sequence Analysis, Human Genome Center, The Institute of Medical Science, The University of Tokyo, Tokyo, 108-8639, Japan

Hidewaki Nakagawa

hidewaki@ims.u-tokyo.ac.jp

Affiliation Laboratory for Genome Sequencing Analysis, RIEKN Center for Integrative Medical Sciences, Yokohama, 230-0045, Japan

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: Y. Shiraishi AF S. Miyano HN. Performed the experiments: Y. Shiraishi AF MF KN AS KM RK HN. Analyzed the data: Y. Shiraishi AF MF HT KAB K. Chiba TA TS TT S. Miyano. Contributed reagents/materials/analysis tools: YK MU KG SA SH Y. Shigekawa S. Marubashi TY OI HA KA HO MY HY MK K. Chayama. Wrote the paper: Y. Shiraishi AF MF S. Miyano HN.