About the Authors

Anke Doyon

anke.doyon@med.uni-heidelberg.de

Affiliation Division of Pediatric Nephrology, Center for Pediatrics and Adolescent Medicine, Heidelberg, Germany

Dagmar-Christiane Fischer

Affiliation Department of Pediatrics, University Hospital Rostock, Rostock, Germany

Aysun Karabay Bayazit

Affiliation Division of Pediatric Nephrology, Cukurova University, School of Medicine, Adana, Turkey

Nur Canpolat

Affiliation Division of Pediatric Nephrology, Istanbul University Cerrahpasa Faculty of Medicine, Istanbul, Turkey

Ali Duzova

Affiliation Division of Pediatric Nephrology, Dpt. of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey

Betül Sözeri

Affiliation Division of Pediatric Nephrology, Ege University Medical Faculty, Izmir, Turkey

Justine Bacchetta

Affiliation Centre de Référence des Maladies Rénales Rares, Hôpital Femme Mère Enfant, Hospices Civils de Lyon, Bron, France

Ayse Balat

Affiliation Department of Pediatric Nephrology, University of Gaziantep, Gaziantep, Turkey

Anja Büscher

Affiliation Division of Pediatric Nephrology, University Children’s Hospital, Essen, Germany

Cengiz Candan

Affiliation Division of Pediatric Nephrology, Istanbul Medeniyet University, Göztepe Training and Research Hospital, Istanbul, Turkey

Nilgun Cakar

Affiliation Diskapi Children’s Hospital, Ankara, Turkey

Osman Donmez

Affiliation Division of Pediatric Nephrology, Uludag University Faculty of Medicine, Bursa, Turkey

Jiri Dusek

Affiliation Pediatric Hospital, University Hospital Motol, Prague, Czech Republic

Martina Heckel

Affiliation University Children’s Hospital, Hamburg, Germany

Günter Klaus

Affiliation KfH Kidney Center for Children, Marburg, Germany

Sevgi Mir

Affiliation Division of Pediatric Nephrology, Ege University Medical Faculty, Izmir, Turkey

Gül Özcelik

Affiliation Department of Pediatric Nephrology, Sisli Educational and Research Hospital, Istanbul, Turkey

Lale Sever

Affiliation Division of Pediatric Nephrology, Istanbul University Cerrahpasa Faculty of Medicine, Istanbul, Turkey

Rukshana Shroff

Affiliation Division of Pediatric Nephrology, Great Ormond Street Hospital, London, United Kingdom

Enrico Vidal

Affiliation Dialysis and Transplantation Department of Pediatrics, Padova, Italy

Elke Wühl

Affiliation Division of Pediatric Nephrology, Center for Pediatrics and Adolescent Medicine, Heidelberg, Germany

Matthias Gondan

Affiliation Department of Psychology, University of Copenhagen, Copenhagen, Denmark

Anette Melk

Affiliations Department of Pediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, Hannover, Germany, Integrated Research and Treatment Center Transplantation (IFB-Tx), Hannover Medical School, Hannover, Germany

Uwe Querfeld

Affiliation Clinic of Pediatric Nephrology, Charite Children’s Hospital, Berlin, Germany

Dieter Haffner

‡ These authors contributed equally to this work.

Affiliation Department of Pediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, Hannover, Germany

Franz Schaefer

‡ These authors contributed equally to this work.

Affiliation Division of Pediatric Nephrology, Center for Pediatrics and Adolescent Medicine, Heidelberg, Germany

for the 4C Study Consortium

Membership of the 4C Study Consortium is listed in the Acknowledgments.

Competing Interests

We have the following interests. This study was partly funded by Pfizer Deutschland GmbH. There are no patents, products in development or marketed products to declare. This does not alter our adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: AD DF DH FS. Performed the experiments: AD DF AKB NCan ADu BS JB ABa ABü CC NCak OD JD MH GK SM GÖ LS RS EV EW AM UQ. Analyzed the data: AD MG. Contributed reagents/materials/analysis tools: DF MG. Wrote the paper: AD DF DH FS.