About the Authors

Young Pil Kim

Contributed equally to this work with: Young Pil Kim, Dongsun Park, Jae Jin Kim

Affiliation Department of Bio-Engineering, Life Science RD Center, Sinil Pharmaceutical Co., Seongnam, South Korea

Dongsun Park

Contributed equally to this work with: Young Pil Kim, Dongsun Park, Jae Jin Kim

Affiliation Department of Physiology, Ajou University School of Medicine, Suwon, South Korea

Jae Jin Kim

Contributed equally to this work with: Young Pil Kim, Dongsun Park, Jae Jin Kim

Affiliations Department of Physiology, Ajou University School of Medicine, Suwon, South Korea, Department of Biomedical Sciences, The Graduate School, Ajou University, Suwon, South Korea

Won-Jae Choi

Affiliation Department of Bio-Engineering, Life Science RD Center, Sinil Pharmaceutical Co., Seongnam, South Korea

Sun Hee Lee

Affiliation Department of Bio-Engineering, Life Science RD Center, Sinil Pharmaceutical Co., Seongnam, South Korea

Seo Yun Lee

Affiliations Department of Physiology, Ajou University School of Medicine, Suwon, South Korea, Department of Biomedical Sciences, The Graduate School, Ajou University, Suwon, South Korea

Soyeon Kim

Affiliations Department of Physiology, Ajou University School of Medicine, Suwon, South Korea, Department of Biomedical Sciences, The Graduate School, Ajou University, Suwon, South Korea

Jee Min Chung

Affiliations Department of Physiology, Ajou University School of Medicine, Suwon, South Korea, Department of Biomedical Sciences, The Graduate School, Ajou University, Suwon, South Korea

Jinseon Jeon

Affiliation Department of Physiology, Ajou University School of Medicine, Suwon, South Korea

Byoung Dae Lee

Affiliation Department of Neuroscience, Kyung Hee University School of Medicine, Seoul, South Korea

Joo-Ho Shin

Affiliation Division of Pharmacology, Department of Molecular Cell Biology, Samsung Biomedical Research Institute, SungKyunKwan University School of Medicine, Suwon, South Korea

Yun-il Lee

Affiliation Well Aging Research Center, Samsung Advanced Institute of Technology (SAIT), Suwon, South Korea

Hyeseong Cho

hscho@ajou.ac.kr (HC); jmlee777@hanafos.com (JL); hckang@ajou.ac.kr (HCK)

These authors also contributed equally to this work.

Affiliations Department of Biomedical Sciences, The Graduate School, Ajou University, Suwon, South Korea, Department of Biochemistry, Ajou University School of Medicine, Suwon, South Korea

Jeong-Min Lee

hscho@ajou.ac.kr (HC); jmlee777@hanafos.com (JL); hckang@ajou.ac.kr (HCK)

These authors also contributed equally to this work.

Affiliation Department of Bio-Engineering, Life Science RD Center, Sinil Pharmaceutical Co., Seongnam, South Korea

Ho Chul Kang

hscho@ajou.ac.kr (HC); jmlee777@hanafos.com (JL); hckang@ajou.ac.kr (HCK)

These authors also contributed equally to this work.

Affiliations Department of Physiology, Ajou University School of Medicine, Suwon, South Korea, Department of Biomedical Sciences, The Graduate School, Ajou University, Suwon, South Korea

Competing Interests

The authors have read the journal's policy. YPK, SHL, WC, and JL are employees of Sinil Pharmaceutical Company and received salary from them. YL is employee of Samsung Advanced Institute of Technology (SAIT) and also received salary from SAIT. There are no products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: HCK JL HC. Performed the experiments: YPK DP JJK SHL WC SYL SK JMC. Analyzed the data: JJ YL. Contributed reagents/materials/analysis tools: BDL JS YL. Wrote the paper: HCK DP YPK.