About the Authors

Giordano Valente

valente@tecno.ior.it

Affiliation Medical Technology Laboratory, Rizzoli Orthopaedic Institute, Bologna, Italy

Lorenzo Pitto

Affiliation Medical Technology Laboratory, Rizzoli Orthopaedic Institute, Bologna, Italy

Debora Testi

Affiliation BioComputing Competence Centre, SCS s.r.l., Bologna, Italy

Ajay Seth

Affiliation Department of Bioengineering, Stanford University, Stanford, California, United States of America

Scott L. Delp

Affiliations Department of Bioengineering, Stanford University, Stanford, California, United States of America, Department of Mechanical Engineering, Stanford University, Stanford, California, United States of America

Rita Stagni

Affiliation Department of Electrical, Electronic and Information Engineering, University of Bologna, Bologna, Italy

Marco Viceconti

Affiliation Department of Mechanical Engineering and INSIGNEO Institute for In Silico Medicine, University of Sheffield, Sheffield, United Kingdom

Fulvia Taddei

Affiliation Medical Technology Laboratory, Rizzoli Orthopaedic Institute, Bologna, Italy

Competing Interests

Debora Testi is affiliated to the BioComputing Competence Centre, SCS s.r.l. commercial company. This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: GV LP FT. Performed the experiments: GV LP. Analyzed the data: GV LP FT. Wrote the paper: GV. Contributed software design and development: GV LP DT AS SLD MV FT. Produced gait analysis data: RS. Edited the manuscript: GV LP DT AS SLD RS MV FT.