About the Authors

Florian Alten

Contributed equally to this work with: Florian Alten, Jeremias Motte

florian.alten@ukmuenster.de

Affiliation Department of Ophthalmology, University of Muenster Medical Center, Muenster, Germany

Jeremias Motte

Contributed equally to this work with: Florian Alten, Jeremias Motte

Affiliation Department of Neurology, University of Muenster Medical Center, Muenster, Germany

Carina Ewering

Affiliation Department of Neurology, University of Muenster Medical Center, Muenster, Germany

Nani Osada

Affiliation Department of Medical Informatics and Biomathematics, University of Muenster, Muenster, Germany

Christoph R. Clemens

Affiliation Department of Ophthalmology, University of Muenster Medical Center, Muenster, Germany

Ella M. Kadas

Affiliation Department of Neurology, Charite University Medicine Berlin, Berlin, German

Nicole Eter

Affiliation Department of Ophthalmology, University of Muenster Medical Center, Muenster, Germany

Friedemann Paul

Affiliations Department of Neurology, Charite University Medicine Berlin, Berlin, German, NeuroCure Clinical Research Center, Berlin, Germany

Martin Marziniak

Affiliation Department of Neurology, University of Muenster Medical Center, Muenster, Germany

Competing Interests

Alten F, Heidelberg Engineering, Novartis, Bayer, Allergan; Motte J, none; Ewering C, none; Osada N, none; Clemens CR, Heidelberg Engineering, Novartis, Bayer, Allergan; Kadas EM, none; Eter N, Heidelberg Engineering, Bayer, Novartis, Allergan, Pfizer, Bausch and Lomb; Paul F, BiogenIdec, Teva, SanofiGenzyme, Merck, Novartis, Heidelberg Engineering; supported by German Research Foundation (DFG Exc 257), German Ministry for Education and Research (BMBF Competence Network Multiple Sclerosis); Marziniak M, none. This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: FA JM NE FP MM. Performed the experiments: FA JM CE MM. Analyzed the data: FA JM EMK NO FP MM. Contributed reagents/materials/analysis tools: NO EMK NE FP MM. Contributed to the writing of the manuscript: FA JM CC NE FP MM.