About the Authors

Luigi Margiotta-Casaluci

Luigi.Margiotta-Casaluci@brunel.ac.uk

Affiliations Institute for the Environment, Brunel University, London, United Kingdom, AstraZeneca, Global Environment, Freshwater Quarry, Brixham, United Kingdom

Stewart F. Owen

Affiliation AstraZeneca, Global Environment, Freshwater Quarry, Brixham, United Kingdom

Rob I. Cumming

Affiliation AstraZeneca, Global Environment, Freshwater Quarry, Brixham, United Kingdom

Anna de Polo

Affiliation Institute for the Environment, Brunel University, London, United Kingdom

Matthew J. Winter

Affiliation AstraZeneca, Global Environment, Freshwater Quarry, Brixham, United Kingdom

Grace H. Panter

Affiliation AstraZeneca, Global Environment, Freshwater Quarry, Brixham, United Kingdom

Mariann Rand-Weaver

Affiliation Biosciences, School of Health Sciences and Social Care, Brunel University, London, United Kingdom

John P. Sumpter

Affiliation Institute for the Environment, Brunel University, London, United Kingdom

Competing Interests

This work was co-funded by the AstraZeneca Global Environment research programme. SFO is an employee of AstraZeneca; RIC, MJW and GHP were also AstraZeneca employees. AstraZeneca is a biopharmaceutical company specialized in the discovery, development, manufacturing and marketing of prescription medicines, including some anxiolytic products. This does not alter our adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: LM-C SFO GHP MR-W JPS. Performed the experiments: LM-C SFO RIC AdP. Analyzed the data: LM-C SFO RIC AdP MJW GHP MR-W JPS. Contributed reagents/materials/analysis tools: SFO RIC MJW GHP MR-W JPS. Contributed to the writing of the manuscript: LM-C. Critical review and revision of the manuscript: SFO AdP MJW GHP MR-W JPS.