Human CD117 (cKit)+ Innate Lymphoid Cells Have a Discrete Transcriptional Profile at Homeostasis and Are Expanded during Filarial Infection

Alexis Boyd; José M. C. Ribeiro; Thomas B. Nutman

doi:10.1371/journal.pone.0108649

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Open Access

Peer-reviewed

Research Article

Human CD117 (cKit)+ Innate Lymphoid Cells Have a Discrete Transcriptional Profile at Homeostasis and Are Expanded during Filarial Infection

Alexis Boyd,

Affiliation Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
José M. C. Ribeiro,

Affiliation Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Thomas B. Nutman

* E-mail: tnutman@niaid.nih.gov

Affiliation Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
⨯

Human CD117 (cKit)+ Innate Lymphoid Cells Have a Discrete Transcriptional Profile at Homeostasis and Are Expanded during Filarial Infection

Alexis Boyd,
José M. C. Ribeiro,
Thomas B. Nutman

Published: September 25, 2014
https://doi.org/10.1371/journal.pone.0108649

About the Authors

Alexis Boyd

Affiliation Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

José M. C. Ribeiro

Affiliation Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

Thomas B. Nutman

* E-mail: tnutman@niaid.nih.gov

Affiliation Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: TN AB JR. Performed the experiments: AB JR. Analyzed the data: AB JR TN. Contributed reagents/materials/analysis tools: AB JR TN. Contributed to the writing of the manuscript: AB JR TN.

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Cytokines
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T cells
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Blood
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Parasitic diseases
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Chemokines
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MicroRNAs
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Eosinophils
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Messenger RNA
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