About the Authors

Rong-Hong Hua

huaronghong@163.com (RHH); buzhigao@caas.cn (ZGB)

Affiliation State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, Heilongjiang, People's Republic of China

Hong Huo

Affiliation State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, Heilongjiang, People's Republic of China

Ye-Nan Li

Affiliation State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, Heilongjiang, People's Republic of China

Yao Xue

Affiliations State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, Heilongjiang, People's Republic of China, College of Life Science, Heilongjiang University, Harbin, Heilongjiang, People's Republic of China

Xiao-Lei Wang

Affiliation State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, Heilongjiang, People's Republic of China

Li-Ping Guo

Affiliation State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, Heilongjiang, People's Republic of China

Bin Zhou

Affiliation Key Laboratory of Animal Diseases Diagnosis and Immunology, Ministry of Agriculture, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, Jiangsu, People's Republic of China

Yong Song

Affiliation College of Life Science, Heilongjiang University, Harbin, Heilongjiang, People's Republic of China

Zhi-Gao Bu

huaronghong@163.com (RHH); buzhigao@caas.cn (ZGB)

Affiliation State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, Heilongjiang, People's Republic of China

Competing Interests

The authors have the following interests: Rong-Hong Hua and Zhi-Gao Bu have the following patent application of BCSFV-E2 cell line for CSF subunit vaccine generation (A recombinant mammalian cell line stably expressing classical swine fever virus E2 protein and its application in preparation of classical swine fever subunit vaccine; application number: 201310300549.8). This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: RHH ZGB. Performed the experiments: RHH HH YNL YX XLW LPG BZ YS. Analyzed the data: RHH ZGB. Contributed reagents/materials/analysis tools: RHH BZ YS ZGB. Contributed to the writing of the manuscript: RHH.