About the Authors

Xingmei Xie

Affiliation Prenatal Diagnostic Center, Guangzhou Women and Children’s Medical Center, Guangzhou, China

Qiaoyi Liang

JessieQY@cuhk.edu.hk

Affiliations Prenatal Diagnostic Center, Guangzhou Women and Children’s Medical Center, Guangzhou, China, Institute of Digestive Disease and Department of Medicine and Therapeutics, State Key Laboratory of Digestive Disease, Li Ka Shing Institute of Health Sciences, CUHK Shenzhen Research Institute, The Chinese University of Hong Kong, Hong Kong

Competing Interests

The authors have submitted patent applications covering the findings of this paper. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: QL. Performed the experiments: XX QL. Analyzed the data: QL. Contributed reagents/materials/analysis tools: QL XX. Contributed to the writing of the manuscript: QL.