About the Authors

Sheila A. Engi

Contributed equally to this work with: Sheila A. Engi, Fábio C. Cruz, Rodrigo M. Leão

Affiliations Laboratory of Pharmacology, Department of Natural Active Principles and Toxicology, School of Pharmaceutical Sciences, Univ. Estadual Paulista-UNESP, Araraquara, SP, Brazil, Joint UFSCar-UNESP Graduate Program in Physiological Sciences, São Carlos, SP, Brazil

Fábio C. Cruz

Contributed equally to this work with: Sheila A. Engi, Fábio C. Cruz, Rodrigo M. Leão

Affiliation Behavioral Neuroscience Branch, Intramural Research Program, National Institute on Drug Abuse, US National Institutes of Health, Department of Health and Human Services, Baltimore, Maryland, United States of America

Rodrigo M. Leão

Contributed equally to this work with: Sheila A. Engi, Fábio C. Cruz, Rodrigo M. Leão

Affiliation Behavioral Neuroscience Branch, Intramural Research Program, National Institute on Drug Abuse, US National Institutes of Health, Department of Health and Human Services, Baltimore, Maryland, United States of America

Luís C. Spolidorio

Affiliation Department of Physiology and Pathology, School of Dentistry of Araraquara, Univ. Estadual Paulista-UNESP, Araraquara, SP, Brazil

Cleopatra S. Planeta

Affiliations Laboratory of Pharmacology, Department of Natural Active Principles and Toxicology, School of Pharmaceutical Sciences, Univ. Estadual Paulista-UNESP, Araraquara, SP, Brazil, Joint UFSCar-UNESP Graduate Program in Physiological Sciences, São Carlos, SP, Brazil

Carlos C. Crestani

cccrestani@yahoo.com.br

Affiliations Laboratory of Pharmacology, Department of Natural Active Principles and Toxicology, School of Pharmaceutical Sciences, Univ. Estadual Paulista-UNESP, Araraquara, SP, Brazil, Joint UFSCar-UNESP Graduate Program in Physiological Sciences, São Carlos, SP, Brazil

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SAE FCC RML CSP CCC. Performed the experiments: SAE FCC RML. Analyzed the data: SAE FCC RML LCS CCC. Contributed reagents/materials/analysis tools: LCS CSP CCC. Contributed to the writing of the manuscript: SAE FCC RML LCS CSP CCC.