About the Authors

I-Hua Wang

Contributed equally to this work with: I-Hua Wang, Hsin-Yi Chen

Affiliation Institute of Biotechnology, National Tsing Hua University, Hsin Chu City, Taiwan

Hsin-Yi Chen

Contributed equally to this work with: I-Hua Wang, Hsin-Yi Chen

Affiliation Institute of Biotechnology, National Tsing Hua University, Hsin Chu City, Taiwan

Yu-Han Wang

Affiliation Institute of Biotechnology, National Tsing Hua University, Hsin Chu City, Taiwan

Ko-Wei Chang

Affiliation Institute of Biotechnology, National Tsing Hua University, Hsin Chu City, Taiwan

Ying-Chieh Chen

Affiliation Institute of Biotechnology, National Tsing Hua University, Hsin Chu City, Taiwan

Chuang-Rung Chang

crchang@life.nthu.edu.tw

Affiliations Institute of Biotechnology, National Tsing Hua University, Hsin Chu City, Taiwan, Department of Medical Science, National Tsing Hua University, Hsin Chu City, Taiwan

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: YHW CRC. Performed the experiments: IHW HYC YHW KWC YCC CRC. Analyzed the data: IHW HYC YHW KWC YCC CRC. Contributed reagents/materials/analysis tools: IHW HYC YHW KWC YCC CRC. Contributed to the writing of the manuscript: CRC.