About the Authors

Chryso Kanthou

C.Kanthou@sheffield.ac.uk

Affiliation Tumour Microcirculation Group, CR-UK/YCR Sheffield Cancer Research Centre, The University of Sheffield, Department of Oncology, School of Medicine, Sheffield, United Kingdom

Gabi U. Dachs

Affiliation Mackenzie Cancer Research Group, Department of Pathology, University of Otago, Christchurch, New Zealand

Diane V. Lefley

Affiliation Tumour Microcirculation Group, CR-UK/YCR Sheffield Cancer Research Centre, The University of Sheffield, Department of Oncology, School of Medicine, Sheffield, United Kingdom

Andrew J. Steele

Affiliation Cancer Sciences Unit, Faculty of Medicine, University of Southampton, Southampton, United Kingdom

Claudia Coralli-Foxon

Affiliation Tumour Microcirculation Group, CR-UK/YCR Sheffield Cancer Research Centre, The University of Sheffield, Department of Oncology, School of Medicine, Sheffield, United Kingdom

Sheila Harris

Affiliation Tumour Microcirculation Group, CR-UK/YCR Sheffield Cancer Research Centre, The University of Sheffield, Department of Oncology, School of Medicine, Sheffield, United Kingdom

Olga Greco

Current address: InVentiv Medical Communications, London, United Kingdom

Affiliation University of Sheffield, Sheffield, United Kingdom

Sofia A. Dos Santos

Affiliation Tumour Microcirculation Group, CR-UK/YCR Sheffield Cancer Research Centre, The University of Sheffield, Department of Oncology, School of Medicine, Sheffield, United Kingdom

Constantino C. Reyes-Aldasoro

Current address: School of Engineering and Mathematical Sciences, City University London, London, United Kingdom

Affiliation University of Sheffield, Sheffield, United Kingdom

William R. English

Affiliation Tumour Microcirculation Group, CR-UK/YCR Sheffield Cancer Research Centre, The University of Sheffield, Department of Oncology, School of Medicine, Sheffield, United Kingdom

Gillian M. Tozer

Affiliation Tumour Microcirculation Group, CR-UK/YCR Sheffield Cancer Research Centre, The University of Sheffield, Department of Oncology, School of Medicine, Sheffield, United Kingdom

Competing Interests

The corresponding author, Chryso Kanthou, is a PLOS ONE Editorial Board member. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: CK GT GD WE. Performed the experiments: CK GD DL AS CCF OG SH SADS. Analyzed the data: CK GT GD CRA WE. Contributed reagents/materials/analysis tools: CRA. Wrote the paper: CK GT GD. Supplied CAIMAN analysis tools and performed analysis of images: CRA.