About the Authors

Mike Clarke

m.clarke@qub.ac.uk

Affiliation All-Ireland Hub for Trials Methodology Research, Queen's University Belfast, Belfast, United Kingdom

Anne Brice

Affiliation James Lind Initiative, Oxford, United Kingdom

Iain Chalmers

Affiliation James Lind Initiative, Oxford, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MC AB IC. Performed the experiments: MC AB IC. Analyzed the data: MC AB IC. Wrote the paper: MC AB IC.