About the Authors

Si-Cai Zhang

Affiliation Institute of Biochemistry and Molecular Biology II, Medical Faculty of the Heinrich-Heine University, Düsseldorf, Germany

Lothar Gremer

Affiliations Institute of Biochemistry and Molecular Biology II, Medical Faculty of the Heinrich-Heine University, Düsseldorf, Germany, Institute of Physical Biology, Heinrich-Heine University, Düsseldorf, Germany, Institute of Complex Systems, ICS-6, Research Center Jülich GmbH, Jülich, Germany

Henrike Heise

Affiliations Institute of Physical Biology, Heinrich-Heine University, Düsseldorf, Germany, Institute of Complex Systems, ICS-6, Research Center Jülich GmbH, Jülich, Germany

Petra Janning

Affiliation Department of Chemical Biology, Max-Planck Institute of Molecular Physiology, Dortmund, Germany

Aliaksei Shymanets

Affiliation Institute of Experimental and Clinical Pharmacology and Toxicology, Tübingen Medical School, Tübingen, Germany

Ion C. Cirstea

Affiliations Institute of Biochemistry and Molecular Biology II, Medical Faculty of the Heinrich-Heine University, Düsseldorf, Germany, Leibniz Institute for Age Research, Jena, Germany

Eberhard Krause

Affiliation Laboratory of Mass Spectrometry, Leibniz Institute of Molecular Pharmacology, Berlin, Germany

Bernd Nürnberg

Affiliation Institute of Experimental and Clinical Pharmacology and Toxicology, Tübingen Medical School, Tübingen, Germany

Mohammad Reza Ahmadian

reza.ahmadian@uni-duesseldorf.de

Affiliation Institute of Biochemistry and Molecular Biology II, Medical Faculty of the Heinrich-Heine University, Düsseldorf, Germany

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SCZ LG HH MRA. Performed the experiments: SCZ LG PJ AS EK. Analyzed the data: SCZ LG PJ EK MRA. Contributed reagents/materials/analysis tools: SCZ LG HH PJ AK ICC EK BN MRA. Contributed to the writing of the manuscript: SCZ MRA.