About the Authors

Glen J. Weiss

glen.weiss@ctca-hope.com

Affiliations Cancer Treatment Centers of America, Goodyear, Arizona, United States of America, The Translational Genomics Research Institute (TGen), Phoenix, Arizona, United States of America

Balaji Ganeshan

Affiliation Institute of Nuclear Medicine, University College London, United Kingdom

Kenneth A. Miles

Affiliation Institute of Nuclear Medicine, University College London, United Kingdom

David H. Campbell

Affiliation Imaging Endpoints Core Lab, Scottsdale, Arizona, United States of America

Philip Y. Cheung

Affiliation The Translational Genomics Research Institute (TGen), Phoenix, Arizona, United States of America

Samuel Frank

Affiliation Virginia G. Piper Cancer Center Clinical Trials at Scottsdale Healthcare, Scottsdale, Arizona, United States of America

Ronald L. Korn

Affiliations Imaging Endpoints Core Lab, Scottsdale, Arizona, United States of America, Virginia G. Piper Cancer Center Clinical Trials at Scottsdale Healthcare, Scottsdale, Arizona, United States of America

Competing Interests

GJW is on the speaker's bureau for Genentech, Pfizer, Celgene, and Eli Lilly, and has received honoraria from Quintiles and Medscape. Sequenom, Inc. provided his lab the LungCarta Panel assay analysis, and had no role in the control of the data and information submitted for publication. RLK is an employee and stockholder in Imaging Endpoints, a core lab that supports clinical trials. BG and KM are shareholders in TexRAD Ltd, a company developing and marketing the tumor textural analysis software described in this manuscript, all other authors had control of the data and information submitted for publication. These disclosures do not alter the authors' adherence to PLOS ONE policies on sharing data and materials. There are no other author disclosures.

Author Contributions

Conceived and designed the experiments: GJW RLK. Performed the experiments: PYC RLK. Analyzed the data: GJW BG KAM RLK. Contributed reagents/materials/analysis tools: DHC PYC SF. Wrote the paper: GJW BG KAM RLK.