About the Authors

Limin Zhou

Affiliation Hubei Maternal and Child Health Hospital, Wuhan, Hubei, P.R. China

Wei Zheng

Affiliation Yichang Humanwell Pharmaceutical Co.,Ltd, Yichang, Hubei, P.R. China

Majing Luo

Affiliation College of Life Sciences, Wuhan University, Wuhan, P.R. China

Jing Feng

Affiliation International school of software, Wuhan University, Wuhan, P.R. China

Zhichun Jin

Affiliation Hubei Maternal and Child Health Hospital, Wuhan, Hubei, P.R. China

Yan Wang

Affiliation Hubei Maternal and Child Health Hospital, Wuhan, Hubei, P.R. China

Dunlan Zhang

Affiliation Hubei Maternal and Child Health Hospital, Wuhan, Hubei, P.R. China

Qiongxiu Tang

Affiliation Hubei Maternal and Child Health Hospital, Wuhan, Hubei, P.R. China

Yan He

heyan@mail.hzau.edu.cn

Affiliation College of Fisheries, Huazhong Agricultural University, Wuhan, P.R. China

Competing Interests

The commercial company (Yichang Humanwell Pharmaceutical Co.,Ltd,), along with any other relating to employment, consultancy, patents, products in development or marketed products etc., have declared that no competing interests and Financial disclosure. This does not alter the authors’ adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: YH. Performed the experiments: LZ WZ ZJ YW DZ QT. Analyzed the data: LZ ML JF. Contributed reagents/materials/analysis tools: YH. Wrote the paper: LZ YH.