About the Authors

Elizabeth Gargon

e.gargon@liv.ac.uk

Affiliation University of Liverpool, Department of Biostatistics, Liverpool, United Kingdom

Binu Gurung

Affiliation University of Liverpool, Department of Biostatistics, Liverpool, United Kingdom

Nancy Medley

Affiliation University of Liverpool, Department of Biostatistics, Liverpool, United Kingdom

Doug G. Altman

Affiliation University of Oxford, Centre for Statistics in Medicine, Botnar Research Centre, Oxford, United Kingdom

Jane M. Blazeby

Affiliation School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom

Mike Clarke

Affiliation Queens University Belfast, Institute of Clinical Sciences, Block B, Royal Hospitals, Belfast, United Kingdom

Paula R. Williamson

Affiliation University of Liverpool, Department of Biostatistics, Liverpool, United Kingdom

Competing Interests

DGA, JB, MC and PRW are members of the COMET Management Group and co-applicants on grants to support COMET and related work. EG is a member of the COMET Management Group and is the COMET Project Co-ordinator. This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: EG PRW. Performed the experiments: EG NM BG. Analyzed the data: EG PRW MC JB DGA. Wrote the paper: EG PRW.