About the Authors

James H. Stein

jhs@medicine.wisc.edu

Affiliation Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America

Asha Asthana

Affiliation Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America

Stevens S. Smith

Affiliation Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America

Megan E. Piper

Affiliation Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America

Wei-Yin Loh

Affiliation Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America

Michael C. Fiore

Affiliation Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America

Timothy B. Baker

Affiliation Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America

Competing Interests

Medications were provided by GlaxoSmithKline. Drs. Smith, Piper, Fiore, and Baker have participated in research studies at the University of Wisconsin that were funded wholly or in part by GlaxoSmithKline and Pfizer. Dr. Fiore also has received research funding from Nabi Pharmaceuticals. There are no patents, products in development or marketed products to declare. This does not alter our adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: AA MF TB JS. Performed the experiments: AA MF MP TB JS. Analyzed the data: JS WL. Contributed reagents/materials/analysis tools: TB SS JS WL. Wrote the paper: AA JS TB.