About the Authors

Dennis Lambrechts

Affiliations Department of Metallurgy and Materials Engineering, KU Leuven, Leuven, Belgium, Prometheus, Division of Skeletal Tissue Engineering Leuven, KU Leuven, Leuven, Belgium

Maarten Roeffaers

Affiliation Center for Surface Chemistry and Catalysis, KU Leuven, Leuven, Belgium

Karel Goossens

Affiliation Department of Chemistry and Biochemistry, The University of Texas at Austin, Austin, Texas, United States of America

Johan Hofkens

Affiliation Molecular Imaging and Photonics, KU Leuven, Leuven, Belgium

Tom Van de Putte

Affiliation TiGenix NV, Leuven, Belgium

Jan Schrooten

Hans.VanOosterwyck@mech.kuleuven.be (HVO); Jan.Schrooten@mtm.kuleuven.be (JS)

Affiliations Department of Metallurgy and Materials Engineering, KU Leuven, Leuven, Belgium, Prometheus, Division of Skeletal Tissue Engineering Leuven, KU Leuven, Leuven, Belgium

Hans Van Oosterwyck

Hans.VanOosterwyck@mech.kuleuven.be (HVO); Jan.Schrooten@mtm.kuleuven.be (JS)

Affiliations Prometheus, Division of Skeletal Tissue Engineering Leuven, KU Leuven, Leuven, Belgium, Biomechanics Section, KU Leuven, Leuven, Belgium

Competing Interests

Dennis Lambrechts is a scholar supported by the agency for Innovation by Science and Technology (IWT-Vlaanderen, project number 090727) via the IWT Baekeland program in which TiGenix NV acts as industrial partner. The purpose of the Baekeland program is to offer researchers the opportunity to carry out PhD research in close collaboration with the industrial sector. The Baekeland program provides support for individual mandates (DL), including cofinancing of operating costs associated with the implementation of the project. The mandate holder, DL, is an employee of KU Leuven and his work activities take place in KU Leuven. Tom Van de Putte is the industrial promoter of DL and employee of TiGenix NV. This however does not alter the authors’ adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: DL MR KG. Performed the experiments: DL KG. Analyzed the data: DL MR KG. Contributed reagents/materials/analysis tools: KG. Wrote the paper: DL. Supervised experimental design and data analysis: JH TVP JS HVO. Reviewed and commented on the manuscript: DL MR KG JH TVP JS HVO.